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| | BMS-1166 HCl Basic information |
| Product Name: | BMS-1166 HCl | | Synonyms: | BMS-1166 HCl;BMS-1166 hydrochloride
(BMS1166 Hcl;BMS1166 HCL;BMS 1166 HCL;BMS-1166 hydrochloride;BMS1166 hydrochloride,BMS 1166 hydrochloride | | CAS: | 2113650-05-6 | | MF: | C36H34Cl2N2O7 | | MW: | 677.58 | | EINECS: | | | Product Categories: | | | Mol File: | 2113650-05-6.mol |  |
| | BMS-1166 HCl Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMSO: soluble | | form | A solid | | color | White to off-white |
| | BMS-1166 HCl Usage And Synthesis |
| Description | BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor. BMS-1166 binds to human PD-L1 and blocks its interaction with PD-1. BMS-1166 alleviates the inhibitory effect of the soluble PD-L1 on the T-cell receptor-mediated activation of T-lymphocytes. Moreover, BMS-1166 was effective in attenuating the inhibitory effect of the cell surface-associated PD-L1. | | target | BMS-1166 hydrochloride is a potent PD-1/PD-L1 immune checkpoint inhibitor. |
| | BMS-1166 HCl Preparation Products And Raw materials |
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