Iminodipropyl dimethanesulfonate 4-toluenesulphonate

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Iminodipropyl dimethanesulfonate 4-toluenesulphonate Basic information
Product Name:Iminodipropyl dimethanesulfonate 4-toluenesulphonate
Synonyms:Iminodipropyl dimethanesulfonate 4-toluenesulphonate;864-T;Improsulfan tosilate;Improsulfan tosylate;Protecton
CAS:32784-82-0
MF:
MW:0
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Mol File:32784-82-0.mol
Iminodipropyl dimethanesulfonate 4-toluenesulphonate Structure
Iminodipropyl dimethanesulfonate 4-toluenesulphonate Chemical Properties
Melting point 113-118°
Safety Information
MSDS Information
Iminodipropyl dimethanesulfonate 4-toluenesulphonate Usage And Synthesis
OriginatorProtecton,Yoshitomi,Japan,1980
DefinitionChEBI: Improsulfan tosylate is an organosulfonic ester.
Manufacturing ProcessA solution of 5 g of bis(3-methylsulfonyloxypropyl)amine hydrochloride in 20 ml of ice water is neutralized with 1N sodium carbonate solution. The resulting amine base is extracted with five 20 ml portions of chloroform. The combined extract is dried over anhydrous sodium sulfate, the solvent is distilled off under reduced pressure, and the residue is dissolved in 20 ml of ethanol. To the ethanol solution is added slowly with stirring under ice cooling a solution of 2.6 g of p-toluenesulfonic acid in 30 ml of ethanol. The white precipitate formed is collected by filtration and recrystallized from ethanol to give 5.0 g of white crystalline bis(3-methylsulfonyloxypropyl)amine p-toluenesulfonate melting at 115°C to 116°C.
Therapeutic FunctionAntitumor
Iminodipropyl dimethanesulfonate 4-toluenesulphonate Preparation Products And Raw materials
Raw materialsSodium carbonate-->p-Toluenesulfonic acid
Tag:Iminodipropyl dimethanesulfonate 4-toluenesulphonate(32784-82-0) Related Product Information
N-Methyl-N,N-bis(3-methylsulfonyloxypropyl)amine 4,4'-biphenyldisulfonate Improsulfan Iminodipropyl dimethanesulfonate 4-toluenesulphonate