N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDE manufacturers
- FG 7142
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- $58.00 / 5mg
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2024-10-28
- CAS:78538-74-6
- Min. Order:
- Purity: 98.81%
- Supply Ability: 10g
- FG 7142
-
- $58.00 / 5mg
-
2024-10-28
- CAS:78538-74-6
- Min. Order:
- Purity: 98.81%
- Supply Ability: 10g
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| N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDE Basic information | Description |
Product Name: | N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDE | Synonyms: | 4-b)indole-3-carboxamide,n-methyl-9h-pyrido(;n-methyl-9h-pyrido(3,4-b)indole-3-carboxamide;FG 7142;N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDE;B-carboline-3-carboxylic acid N-*methylamide;N-METHYL-B-CARBOLINE-3-CARBOXAMIDE (FG-7 142);beta-carboline-3-carboxylic acid N-methylamide;β-Carboline-3-carboxylic acid N-methylamide | CAS: | 78538-74-6 | MF: | C13H11N3O | MW: | 225.25 | EINECS: | | Product Categories: | GABA/Glycine receptor | Mol File: | 78538-74-6.mol | |
| N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDE Chemical Properties |
Boiling point | 576.3±30.0 °C(Predicted) | density | 1.328±0.06 g/cm3(Predicted) | storage temp. | 2-8°C | solubility | ethanol: 1 mg/mL | form | A crystalline solid | pka | 13.44±0.46(Predicted) | color | light tan |
WGK Germany | 3 | RTECS | UU9780100 |
| N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDE Usage And Synthesis |
Description | FG 7142 (ZK 39106; LSU-65) is a nonselective benzodiazepine inverse agonist with high affinity (Ki= 91 nM) for the α1 subunit-containing GABAA receptor. FG 7142 also modulates GABA-induced chloride flux (EC50=137 nM) at GABAA receptors expressing the α1 subunit. FG 7142 increases tyrosine hydroxylation and leads to upregulation of β-adrenergic receptors in mouse cerebral cortex. | Uses | FG 7142 is a benzodiazepine inverse agonist anxiogenic compound. | Definition | ChEBI: N-methyl-9H-pyrido[3,4-b]indole-3-carboxamide is a member of beta-carbolines. | Biological Activity | Inverse agonist and anxiogenic agent. Increases tyrosine hydroxylation and causes upregulation of β -adrenoceptors in mouse cerebral cortex. | Biochem/physiol Actions | Benzodiazepine inverse receptor agonist; potent anxiogenic agent. | storage | Store at RT |
| N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDE Preparation Products And Raw materials |
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