(S)-(+)-2-HYDROXY-3-METHYLBUTYRIC ACID

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CAS:17407-55-5
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CAS:17407-55-5
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Products Intro: Product Name:(S)-(+)-2-Hydroxy-3- Methylbutanoic Acid
CAS:17407-55-5
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(S)-(+)-2-HYDROXY-3-METHYLBUTYRIC ACID manufacturers

(S)-(+)-2-HYDROXY-3-METHYLBUTYRIC ACID Basic information
Product Name:(S)-(+)-2-HYDROXY-3-METHYLBUTYRIC ACID
Synonyms:(S)-(+)-2-HYDROXY-3-METHYLBUTANOIC ACID;(S)-(+)-2-HYDROXY-3-METHYLBUTYRIC ACID;(S)-2-HYDROXY-3-METHYLBUTYRIC ACID;L-ALPHA-HYDROXYISOVALERIC ACID;2S-HYDROXY-3-METHYL-BUTANOIC ACID;2-HYDROXY-3-METHYLBUTYRIC ACID;3-METHYL-2-HYDROXY-BUTANOIC ACID;(S)-(+)-2-HYDROXY-3-METHYLBUTYRIC ACID, 99% (99% EE/GLC)
CAS:17407-55-5
MF:C5H10O3
MW:118.13
EINECS:605-704-7
Product Categories:pharmacetical;Aliphatics;Carboxylic Acids;chiral;Carboxylic Acids
Mol File:17407-55-5.mol
(S)-(+)-2-HYDROXY-3-METHYLBUTYRIC ACID Structure
(S)-(+)-2-HYDROXY-3-METHYLBUTYRIC ACID Chemical Properties
Melting point 68-70 °C (lit.)
Boiling point 124-125 °C/13 mmHg (lit.)
density 1.136
refractive index 1.4641 (estimate)
Fp 112℃
storage temp. Sealed in dry,Room Temperature
solubility DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 10 mg/ml
form Powder
pka3.87±0.16(Predicted)
color White
optical activity[α]20/D +19°, c = 1 in chloroform
BRN 1721140
CAS DataBase Reference17407-55-5(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
3-10
Hazard Note Irritant
HS Code 29181990
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
(S)-(+)-2-HYDROXY-3-METHYLBUTYRIC ACID Usage And Synthesis
Chemical Propertieswhite fine crystalline powder
UsesA useful chiral building block for peptide synthesis. Used in the preparation of the cytotoxic didemnin cyclopeptides and of the antineoplastic agent dolastatin 15.
DefinitionChEBI: (S)-2-hydroxy-3-methylbutyric acid is the S-enantiomer of 2-hydroxy-3-methylbutyric acid. It is used as a chiral building block for peptide synthesis. It has a role as a chiral reagent and a human metabolite. It is a conjugate acid of a (S)-2-hydroxy-3-methylbutyrate. It is an enantiomer of a (R)-2-hydroxy-3-methylbutyric acid.
(S)-(+)-2-HYDROXY-3-METHYLBUTYRIC ACID Preparation Products And Raw materials
Raw materialsSulfuric acid-->Sodium nitrite-->Ammonium sulfate-->L-Valine
Tag:(S)-(+)-2-HYDROXY-3-METHYLBUTYRIC ACID(17407-55-5) Related Product Information
Azadirachtin MONOCROTALINE D-(-)-PANTOLACTONE (S)-(+)-2-HYDROXY-3-METHYLBUTYRIC ACID PICROTOXIN AZADIRACHTIN H(SH) RETRORSINE PICROTOXININ (S)-(+)-2-Amino-3-hydroxy-3-methylbutanoic acid (R)-Methyl 2-hydroxy-3-methylbutanoate 4-Hydroxy-2-methylbutyric acid lactone,4-Hydroxy-2-methylbutyric acid lactone 3-Hydroxy-2-methylbutyric acid,3-Hydroxy-2-methylbutyric acid D-beta-Hydroxyvaline (2R)-2-Hydroxy-3-methylbutyric acid 2-HYDROXY-2-METHYLBUTYRIC ACID,2-HYDROXY-2-METHYLBUTYRIC ACID beta-Hydroxyisovaleric Acid 2-(S)-Hydroxy-3-methylbutyric acid methyl ester,2-(S)-Hydroxy-3-methylbutyric acid methyl ester 4,4,4-TRIFLUORO-3-HYDROXY-3-METHYLBUTYRIC ACID,4,4,4-TRIFLUORO-3-HYDROXY-3-METHYLBUTYRIC ACID