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Postion:Product Catalog >API>Antineoplastic agents>Tinib Antineoplastic drugs>Imatinib Mesylate 220127-57-1
Imatinib Mesylate  220127-57-1
  • Imatinib Mesylate  220127-57-1

Imatinib Mesylate 220127-57-1

Price $10
Package 1KG
Min. Order: 10G
Supply Ability: 10MT
Update Time: 2019-01-15

Product Details

Product Name: Imatinib Mesylate 220127-57-1 CAS No.: 220127-57-1
Min. Order: 10G Purity: 99%
Supply Ability: 10MT Release date: 2019/01/15
MF : C30H35N7O4S Usage: Anti tumor drugs

1. Quick Details:

 

Product Name: Imatinib Mesylate

Synonyms : GLIVEC;GLEEVEC;IMATINIB METHANESULFONATE;CGP-57148B;4-[(4-methylpiperazin-1-yl)methyl]-n-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide methanesulfonate;4-[(4-methyl-1-piperazinyl)methyl]-n-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-benzamide monomethanesulfonate;STI-571;IMATINIB BASE(IMA-3)

CAS NO.: 220127-57-1

Molecular Formula : C30H35N7O4S

Molecular weight: 589.71

Documents: GMP

Quality: 99%up by HPLC

Usage: Anti tumor drugs

Storage: Preserve in well-closed containers, keep from light and store below 30 °C

 

2. Product Description:

 

Chemical name

Imatinib Mesylate

CAS NO.

220127-57-1

Synonyms

GLIVEC;GLEEVEC;IMATINIB METHANESULFONATE;CGP-57148B;4-[(4-methylpiperazin-1-yl)methyl]-n-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide methanesulfonate;4-[(4-methyl-1-piperazinyl)methyl]-n-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-benzamide monomethanesulfonate;STI-571;IMATINIB BASE(IMA-3)

Melting point

183-185°C

Molecular Formula

C30H35N7O4S

Molecular Weight

589.71

Boiling Point

754.9 °C at 760 mmHg

Flash point

410.3 °C

Appearance

Off-white solid

Application

Imatinib is used to treat chronic myelogenous leukemia (CML), gastrointestinal stromal tumors (GISTs) and a number of other malignancies

 

3. Application:

 

A tyrosine kinase inhibitor. Highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL)

Imatinib Mesylate is orally bioavailability mesylate salt of Imatinib, which is a multi-target inhibitor of v-Abl, cKit and PDGFR with IC50 of 0.6 μM, 0.1 μM and 0.1 μM, respectively. Imatinib also known as Gleevec, Glivec, CGP-57148B, STI-571 & Imatinib.

 

4. Specification:

 

COA

Item

Acceptance criteria

Result

Appearance

White or almost white powder

white powder

Solubility

Easy to dissolve in the water

Complies

Identification

High-performance liquid chromatograph

HPLC

Almost the same

Infrared absorption

Almost the same

Melting point

222-227°C

223-224º°C

Water

≤0.5%

0.2%

Heavy metals

≤10ppm

Complies

Residue on ignition

≤0.1%

0.03%

Related impurity

Sigle impurity≤0.5%

0.07%

Total impurity no more than 1.0%

0.11%

HPLC assay

98.0%~102.0%

99.9%

 

 

 

Advantages:

 

 

Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is our philosophy. We have Flexible and Untraceable payment terms. As a leading manufacture, our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries.


1. Quality.Every batch of steroid powders have tobetested by our QC(quality control) before they are allowed to sell.


2 . Delivery We have stock, so we can delivery quickly at the very day when receive the payment. Within 24 hours after receiving the payment Lead time 4 or 7 days.


3 . Discreet package Safelyand Professionally Disguised Package Guaranteed. For your safety and to insure delivery all products will be packed in a discreet way to prevent any suspicions, no steroids related name will appear on the parcels. high successful delivery rate

4 . Warm after-sale service Any of your question would be solved for the first as soon as possible.

 

 

Imatinib Mesylate  220127-57-1 Pharmaceutical Raw Materials

Imatinib Mesylate  220127-57-1 Pharmaceutical Intermediate

Imatinib Mesylate  220127-57-1  Raw Chemical Product

Imatinib Mesylate  220127-57-1  Supplier & manufactuer 

Company Profile Introduction

Hubei XinRunde Chemical Co., Ltd covers an area of 95 acres, the proposed construction of the plant will be GMP standards, the factory environment clean and tidy, rational layout, with large and medium-sized production workshop and repocessed shop. It is equipped with advanced equipment quality inspection and research center. Those products of both quality and technical content have reached the domestic advanced level. Products sell well all over the country and exported to Europe and the United States and Southeast Asia,and so on.

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