Product Name:TPP-1
CAS No.: 2426685-25-6
Synonyms:有效抑制剂多肽TPP-1
Catalog No.:218P432
Brand:HongTide(上海鸿肽生物)
Description:TPP-1 是PD-1/PD-L1相互作用的有效抑制剂多肽,序列中含有22个氨基酸。TPP-1 与 PD-L1 特异性高亲和力结合 (KD=95 nM)。动物模型中,TPP-1 通过再激活 T 细胞功能抑制肿瘤生长。在异种移植物小鼠模型中,TPP-1处理的小鼠的肿瘤生长比对照组低56%-71%。
TPP-1 is an effective inhibitor peptide of PD-1/PD-L1 interaction, with a sequence containing 22 amino acids. TPP-1 binds specifically to PD-L1 with high affinity (KD=95 nM). In animal models, TPP-1 inhibits tumor growth by reactivating T cell function. In the xenograft mouse model, the tumor growth of TPP-1 treated mice was 56% -71% lower than that of the control group.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | SGQYASYHCWCWRDPGRSGGSK |
Sequence(3-letter code) | H-Ser-Gly-Gln-Tyr-Ala-Ser-Tyr-His-Cys-Trp-Cys-Trp-Arg-Asp-Pro-Gly-Arg-Ser-Gly-Gly-Ser-Lys-OH |
Peptide Structure | |
Molecular Formula | C107H150N34O32S2 |
Molecular Weight | 2488.67 |
订购联系方式:
上海鸿肽生物科技有限公司
手机: +86-18018095145 (同微信号)
QQ: 3259098395
邮箱:sales1@hongtide.com
关键字: 2426685-25-6;有效抑制剂多肽TPP-1;TPP-1;多肽;多肽合成;
上海鸿肽生物科技有限公司(简称:鸿肽生物)是一家以多肽以及多肽上下游产品研发、生产、销售以及技术转让为主要业 务科技公司。公司现有产品涵盖:定制多肽、目录多肽、氨基酸衍生物、小分子化合物;公司自成立以来,秉持“用质量作船, 以服务为帆,为科研服务”的企业理念,为国内外众多科研工作者提供了优质的服务及产品。