Human B7-H5 / Gi24 / VISTA Protein, His Tag (MALS verified)
分子别名(Synonym)
B7-H5,SISP1,Gi24,VISTA
表达区间及表达系统(Source)
Human B7-H5, His Tag (B75-H52H0) is expressed from human 293 cells (HEK293). It contains AA Phe 33 - Ala 194 (Accession # AAH20568).
Predicted N-terminus: Phe 33
蛋白结构(Molecular Characterization)
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This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 20.0 kDa. The protein migrates as 33-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
内毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
纯度(Purity)
>90% as determined by SDS-PAGE.
>95% as determined by SEC-MALS.
制剂(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.
Contact us for customized product form or formulation.
重构方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存储(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
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背景(Background)
血小板受体Gi24,也称为B7-H5和应激诱导分泌蛋白-1(Sisp-1),是一种在人类中由C10orf54基因编码的蛋白质,该基因含有1个Ig样(免疫球蛋白样)结构域。至于C10orf54基因,C10orf54似乎与BMP-4呈正相互作用,增强BMP信号传导和ESCs从未分化状态向分化状态的转变。人C10orf54被MT1-MMP进行蛋白水解切割,产生可溶性30kDa细胞外片段和25-30kDa膜结合片段。
关键字: B7-H5;B7-H5蛋白;B7-H5重组蛋白;ACRO;百普赛斯;
百普赛斯集团ACROBiosystems Group(股票代码:301080)是成立于2010年的跨国生物科技公司,是为全球生物医药、健康产业领域提供关键生物试剂产品及解决方案的行业平台型基石企业。2021年在创业板上市。百普赛斯集团业务遍布全球,横跨亚洲、北美洲、欧洲,在中国、美国、瑞士等12个城市设有办公室、研发中心及生产基地。目前累计服务客户超6000家,与全球Top 20医药企业均建立了长期、稳定的合作伙伴关系。集团旗下拥有品牌ACROBiosystems百普赛斯、bioSeedin柏思荟、Condense Capital垦拓资本和ACRODiagnostics百斯医学等。