AMG-510是有效的KRAS G12C共价抑制剂,具有潜在的抗肿瘤活性。该AMG510是手性化合物。
IN VIVO: In preclinical tumor models, AMG-510 rapidly and irreversibly binds to KRAS G12C, providing durable suppression of the mitogen-activated protein kinase (MAPK) signaling pathway. AMG-510 (orally; once daily) is capable of inducing tumor regression in mouse models of KRAS G12C cancer[3].
上海晴宜生物科技有限公司
联系商家时请提及chemicalbook,有助于交易顺利完成!