Thianaphthene: A Versatile Chemical Compound
Jul 31,2024
Introduction
Thianaphthene, also known as benzothiophene, is a significant organic compound in the field of chemistry, particularly known for its presence in coal tar and crude oil. It has the chemical formula C8H6S, and its molecular structure comprises a benzene ring fused with a thiophene ring. As a member of the thiophene family, Thianaphthene holds substantial importance due to its unique properties and various applications in the chemical industry.
Figure 1 Characteristics of Thianaphthene
Properties
Thianaphthene exhibits several intriguing properties that make it a valuable compound for research and industrial applications. It appears as a white to pale yellow crystalline solid and has a characteristic odor. The compound has a melting point of approximately 32-35°C and a boiling point of around 222°C. Its solubility in water is quite low, but it is soluble in organic solvents such as ethanol, ether, and benzene.
One of the critical aspects of Thianaphthene is its stability. It is relatively stable under standard temperature and pressure conditions but can undergo reactions typical of aromatic compounds. It participates in electrophilic substitution reactions, which is a characteristic feature of aromatic compounds. Thianaphthene's reactivity is influenced by the sulfur atom in the thiophene ring, contributing to its unique chemical behavior.
Major Components
Thianaphthene's molecular structure includes two fused rings: a benzene ring and a thiophene ring. This fusion imparts distinct electronic properties to the molecule, making it a subject of interest in organic chemistry. The benzene ring provides aromatic stability, while the thiophene ring, with its sulfur atom, introduces different electronic characteristics compared to purely carbon-based aromatic compounds.
The sulfur atom in the thiophene ring is crucial, as it can participate in various chemical reactions, including oxidation and substitution reactions. This makes Thianaphthene a versatile compound in synthetic chemistry. Additionally, the presence of the sulfur atom influences the compound's electronic distribution, affecting its reactivity and interactions with other molecules.
Applications
Thianaphthene has a wide range of applications, primarily due to its unique chemical structure and properties. One of its significant uses is as a precursor in the synthesis of other organic compounds. Its ability to undergo electrophilic substitution reactions makes it a valuable starting material for creating more complex molecules, including pharmaceuticals, agrochemicals, and dyes.
In the pharmaceutical industry, Thianaphthene derivatives are investigated for their potential therapeutic properties. Compounds containing the benzothiophene moiety have shown promise in treating various diseases, including cancer and infectious diseases. The sulfur atom in the thiophene ring is believed to contribute to the biological activity of these compounds, making them attractive candidates for drug development.
Another critical application of Thianaphthene is in the field of materials science. Its electronic properties make it suitable for use in organic electronic devices, such as organic light-emitting diodes (OLEDs) and organic photovoltaics (OPVs). Researchers are exploring the use of Thianaphthene-based materials to improve the efficiency and performance of these devices, contributing to advancements in renewable energy technologies.
Furthermore, Thianaphthene is used in the production of specialty chemicals and intermediates. Its reactivity and ability to form stable aromatic compounds make it a valuable component in the synthesis of various industrial chemicals, including antioxidants, stabilizers, and polymer additives. The versatility of Thianaphthene in chemical synthesis underscores its importance in multiple industrial sectors.
Storage Methods
Proper storage of Thianaphthene is essential to maintain its stability and ensure safety in handling. As a crystalline solid with low solubility in water, Thianaphthene should be stored in a cool, dry place, away from direct sunlight and sources of ignition. It is advisable to store it in tightly sealed containers to prevent contamination and moisture absorption, which could affect its chemical integrity.
Safety precautions are crucial when handling Thianaphthene. Although it is relatively stable, it should be handled with care to avoid exposure to skin and eyes. Protective equipment, such as gloves and safety goggles, should be used when working with the compound. In case of spills or accidental exposure, it is important to follow proper safety protocols and seek medical attention if necessary.
Additionally, it is essential to store Thianaphthene away from incompatible materials, such as strong oxidizing agents, which could trigger hazardous reactions. Ensuring proper ventilation in storage areas can help minimize the risk of inhalation and exposure to vapors, maintaining a safe working environment.
Conclusion
Thianaphthene, with its unique structure and properties, stands out as a valuable compound in the field of chemistry. Its applications range from serving as a precursor in organic synthesis to contributing to advancements in pharmaceuticals and materials science. Proper storage and handling are crucial to ensure its stability and safety in various industrial and research settings.
Reference
[1] Blicke F F, Sheets D G. Derivatives of Thianaphthene. I1[J]. Journal of the American Chemical Society, 1948, 70(11): 3768-3770.
[2] Taraymovich E S, Enakieva Y Y, Mitasova Y V, et al. Thianaphthene-Annulated Tetrapyrazinoporphyrazines?[J]. Макрогетероциклы, 2010, 3(1): 48-50.
- Related articles
- Related Qustion
- Synthesis of Benzothiophene Jan 27, 2022
Benzothiophene is constituted by fusion of the benzene ring with the thiophene ring. There are two possible methods of fusion of the benzene ring with two different sites, namely 2,3- or [b] and 3,4- or [c] sites of the thiophene ring and a
N,O-Dimethylhydroxylamine hydrochloride enhances dental materials, acts as antimicrobial in periodontal care, and improves biomaterial integration, with safety precautions essential.....
Jul 31,2024APIPromethazine hydrochloride is a white to faint yellow, crystalline powder. It is practically odorless and has a bitter taste.....
Jul 31,2024APIThianaphthene
95-15-8You may like
- Thianaphthene
-
- $0.00 / 25kg
- 2024-08-24
- CAS:95-15-8
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 50000KG/month
- Thianaphthene
-
- $5.00 / 1KG
- 2024-08-20
- CAS:95-15-8
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 10000kg
- thianaphthene
-
- $0.00 / 1Kg
- 2024-04-08
- CAS:95-15-8
- Min. Order: 1Kg
- Purity: 99.9%
- Supply Ability: 200tons