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Тегасерод

Тегасерод структура
145158-71-0
CAS №
145158-71-0
Химическое название:
Тегасерод
английское имя:
Tegaserod
Синонимы:
TEGASEROD;Tegaserode;Tegaserod USP/EP/BP;2-[(5-methoxy-1h-indol-3-yl)methylene]-n-pentylhydrazine-carboximidamide;Hydrazinecarboximidamide, 2-[(5-methoxy-1H-indol-3-yl)methylene]-N-pentyl-;(E)-2-((5-methoxy-1H-indol-3-yl)methylene)-N-pentylhydrazine-1-carboximidamide;Tegaserod D10Q: What is Tegaserod D10 Q: What is the CAS Number of Tegaserod D10;Tegaserod 13CD3Q: What is Tegaserod 13CD3 Q: What is the CAS Number of Tegaserod 13CD3;Tegaserod D11 (Major-D10)Q: What is Tegaserod D11 (Major-D10) Q: What is the CAS Number of Tegaserod D11 (Major-D10)
CBNumber:
CB0225423
Формула:
C16H23N5O
молекулярный вес:
301.39
MOL File:
145158-71-0.mol

Тегасерод атрибут

Температура плавления: 155°
Температура кипения: 470.6±48.0 °C(Predicted)
плотность: 1.18
температура хранения: 2-8°C
форма: Solid
пка: 15.81±0.30(Predicted)
цвет: White to off-white
Справочник по базе данных CAS: 145158-71-0(CAS DataBase Reference)
FDA UNII: 458VC51857
Код УВД: A06AX06

Заявления о рисках и безопасности

Коды опасности Xi
Заявления о рисках 20/21/22-36/37/38
Заявления о безопасности 36/37-36-26

Тегасерод химические свойства, назначение, производство

Использование

Treatment of gastrointestinal motility disorders (selective serotonin 5HT4antagonist).

Показания

Tegaserod (Zelnorm) is serotonin-4 (5-HT4) receptor agonists that stimulate GI motility.

Клиническое использование

Tegaserod is being developed as a treatment for constipation- predominant irritable bowel syndrome (IBS). Within the first week, patients treated with tegaserod had significant improvements in abdominal pain and discomfort, constipation, and overall well-being. Efficacy was maintained throughout the treatment period. Tegaserod also demonstrated significant improvements in the three bowel-related assessments (stool frequency, stool consistency, and straining) within the first week, and these improvements were sustained throughout the treatment period. The most common adverse events reported thus far are headache and diarrhea.

Тегасерод препаратная продукция и сырье

сырьё

препарат


Тегасерод поставщик

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