Фурфуриламин химические свойства, назначение, производство
Химические свойства
Furfurylamine is a colorless to light yellow aromatic amine in liquid form with an ammonia odor. Miscible with water, soluble in ethanol, ether. Deteriorates in air by absorbing carbon dioxide. Derived from furfural based on corn cobs, this green chemistry has proven useful in engine cleaners, and as an intermediate for pharmaceutical, industrial and agricultural chemicals.
Использование
Furfurylamine is used as a water miscible solvent and as an intermediate in manufacturing pharmaceuticals like diuretics, antihypertensive, and antiseptic agents.
Furfurylamine also has use in the synthesis of Barmastine.
2-Furfurylamine is used in the synthesis of 2-Amino-N-(2-furylmethyl)propanamide, as a novel alanylglycine equivalent synthesized by bacilysin synthetase.
Общее описание
Furfurylamine appears as a colorless liquid. About the same density as water. Used as a corrosion inhibitor and to make soldering flux.
Реакции воздуха и воды
Highly flammable. Soluble in water.
Профиль реактивности
Amines, such as Furfurylamine, are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.
Опасность
Flammable, moderate fire risk.
Угроза здоровью
May cause toxic effects if inhaled or ingested/swallowed. Contact with substance may cause severe burns to skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.
Пожароопасность
Flammable/combustible material. May be ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.
Профиль безопасности
Poison by
intraperitoneal route. A skin,eye, and
mucous membrane irritant. A dangerous fire
hazard when exposed to heat or flame; can
react with oxidizing materials. To fight fire,
use foam, CO2, drp chemical. When heated
to decomposition it emits toxic fumes of NOx. See also MINES.
Фурфуриламин препаратная продукция и сырье
сырьё
препарат