3 3' 5-TRIIODO-L-THYRONINE SODIUM SALT&
3 3' 5-TRIIODO-L-THYRONINE SODIUM SALT& атрибут
| Температура плавления: |
205 °C (dec.)(lit.) |
| температура хранения: |
Store at -20°C |
| растворимость: |
ДМФ: 0,25 мг/мл, ДМФ:PBS (рН 7,2) (1:1): 0,5 мг/мл, ДМСО: 1 мг/мл |
| форма: |
Кристаллическое твердое вещество |
| оптическая активность: |
[α]22/D +21.5°, c = 2 in 1 N HCl: ethanol, 1:2 |
Заявления о рисках и безопасности
| Заявления о безопасности |
22-24/25 |
| WGK Германия |
3 |
3 3' 5-TRIIODO-L-THYRONINE SODIUM SALT& химические свойства, назначение, производство
Описание
3,3'',5-Triiodo-L-thyronine (T3) is a thyroid hormone. It is produced by 5''-monodeiodination of the prohormone thyroxine (T4) in various tissues, including liver and kidney. T3 is an agonist of thyroid hormone receptors TRα and TRβ (Kis = 2.3 nM for both) that modulates diverse biological properties, including metabolism, cardiac function, growth, and redox signaling. It also functions as an inhibitor of L-type amino acid transporter 1 (LAT1), inhibiting LAT1-mediated leucine uptake in HEK293 cells when used at a concentration of 10 μM.
3 3' 5-TRIIODO-L-THYRONINE SODIUM SALT& препаратная продукция и сырье
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3 3' 5-TRIIODO-L-THYRONINE SODIUM SALT& поставщик
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