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Пралморелин

Пралморелин структура
158861-67-7
CAS №
158861-67-7
Химическое название:
Пралморелин
английское имя:
GHRP-2
Синонимы:
GHRP-2;GHRP;CHRP-2;GHRP-2 ACETATE;GHCA;EIF3A;d-ala-β-(2-naphthyl)-d-ala-trp-d-phe-lys amide;-2;-2;p-ERK1
CBNumber:
CB1104514
Формула:
C45H55N9O6
молекулярный вес:
817.97
MOL File:
158861-67-7.mol

Пралморелин атрибут

Температура плавления: 149 - 151°C
Температура кипения: 1265.3±65.0 °C(Predicted)
плотность: 1.270±0.06 g/cm3(Predicted)
температура хранения: −20°C
растворимость: ДМСО (Мало растворим, обработанный ультразвуком), вода (Мало растворим)
пка: 13.40±0.46(Predicted)
форма: лиофилизированный порошок
цвет: От белого до бежевого
Стабильность:: Hygroscopic
ИнЧИКей: HRNLPPBUBKMZMT-RDRUQFPZSA-N
SMILES: C(N)(=O)[C@H](CCCCN)NC(=O)[C@@H](CC1=CC=CC=C1)NC(=O)[C@H](CC1C2=C(C=CC=C2)NC=1)NC(=O)[C@H](C)NC(=O)[C@@H](CC1=CC=C2C(=C1)C=CC=C2)NC(=O)[C@@H](C)N
Справочник по базе данных CAS: 158861-67-7(CAS DataBase Reference)
FDA UNII: E6S6E1F19M

Заявления о рисках и безопасности

WGK Германия 3

Пралморелин химические свойства, назначение, производство

Описание

Pralmorelin (also known as KP-102, GPA-748, GHRP-2, and Growth Hormone Releasing Peptide-2)  is a potent GH secretagogue in development as a diagnostic agent for growth hormone deficiency and for the treatment of pituitary disorders and GH deficiency. It acts as signal molecules that are involved in the control of cell growth and differentiation.

Использование

Growth hormone releasing factor. Pralmorelin is a growth hormone secretagogue that acts on the pituitary gland and the hypothalamus to stimulate and amplify pulsatile growth hormone release.

преимущество

Regulation of blood pressure, increased strength and healing, reduced injury, increased cell rejuvenation, increase in lean muscle mass and stronger bones.

Биохимия/физиол Действия

Pralmorelin, also known as Growth hormone-releasing peptide 2 or GHRP-2, is an orally-active, synthetic peptide analogue of met-enkephalin that acts as a ghrelin/growth hormone secretagogue receptor (GHSR) agonist to selectively stimulate the ghrelin receptor and cause growth hormone release. Pralmorelin (GHRP-2) has been used clinically for the assessment of growth hormone deficiency (GHD), It has also been shown to have anti-inflammatory activity.

Побочные эффекты

No side effects or toxicities were observed. Thus, GHRP-2 is well tolerated and can stimulate GH secretion. Formulations or routes of administration that allow for a longer duration of action will likely be needed to use GHRP-2 in therapy[1].

Пралморелин препаратная продукция и сырье

сырьё

препарат


Пралморелин поставщик

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