Fluazinam химические свойства, назначение, производство
Описание
Fluazinam, with a LogP of 3.56, has very low
solubility in water (1.7 mgL?1, pH6.8, 25?C) but higher
solubilities in organic solvents (e.g., acetone 470 g/L,
dichloromethane 330 g/L, ethanol 150 g/L, all at 20 ?C).
The active ingredient forms light yellow crystals with an
MP of 115 to 117 ?C and has a vp of 1.5 mPa (25 ?C). The
compound is stable to acid, alkali, and heat (5).
Химические свойства
yellow crystal mp 115 ~ 117°C
Использование
Fluazinam is a broad spectrum fungicide. Fluazinam is commonly used for control of Sclerotinia blight and other soilborne pathogens of peanut as well for the control of potato blight.
Определение
ChEBI: Fluazinam is a member of the class of aminopyridines that is 2-amino-5-(trifluoromethyl)pyridine in which one of the amino hydrogens is replaced by a 3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl group. A fungicide used to control grey mould, downy mildew and other fungal pathogens. It has a role as an apoptosis inducer, an allergen, a xenobiotic, an environmental contaminant and an antifungal agrochemical. It is a C-nitro compound, a chloropyridine, an aminopyridine, a secondary amino compound, a member of monochlorobenzenes and a member of (trifluoromethyl)benzenes.
Общее описание
Fluazinam is a 2,6-dinitroaniline protectant fungicide, which belongs to the pyridinamine group. It can mostly find applications in agriculture.
Опасность
Moderately toxic by ingestion and inhalation. A reproductive hazard.
Сельскохозяйственное использование
Fungicide: Used to control Sclerotinia blight on peanuts and
late blight and white mold on potatoes.
Торговое название
FLUAZINAM 50 WP®; FROWNCIDE®;
IKF-1216®; ICIA-192®; OMEGA; PP-192®; SHIRLAN®
Контактные аллергены
Fluazinam is a pesticide with a broad spectrum of anti fungal activity. It caused sensitization in employees in
the tulip bulb industry and in farmers. Fluazinam
induced contact dermatitis in a worker in a plant where
it was manufactured.
Профиль безопасности
Moderately toxic by
ingestion and inhalation. Experimental
reproductive effects. When heated to
decomposition it emits toxic vapors of NOx,
F-, and Cl-.
Метаболический путь
Fluazinam may typically be applied to crops of potatoes using up to 10
applications each of 150 g ha-1. Routes of degradation involve ring
hydroxylation in aerobic soils and reduction of the nitro groups in flooded
soils. A large amount of unextractable residue was observed. In potatoes
and rats, important reactions involve the reduction of nitro groups and
the formation of conjugates. In plants, the trifluoromethyl substituents are
hydrolysed to carboxylic acid groups. Most of the information presented
below was taken from an evaluation of the fungicide published by the UK
Pesticide Safety Directorate (PSD, 1994).
Fluazinam препаратная продукция и сырье
сырьё
препарат