N-EPSILON-ACETYL-L-LYSINE
N-EPSILON-ACETYL-L-LYSINE атрибут
| Температура плавления: |
250 °C (dec.)(lit.) |
| Температура кипения: |
323.23°C (rough estimate) |
| плотность: |
1.1793 (rough estimate) |
| показатель преломления: |
1.4500 (estimate) |
| температура хранения: |
-20°C |
| растворимость: |
Водная основа (немного), вода (немного) |
| форма: |
пудра |
| пка: |
2.53±0.24(Predicted) |
| цвет: |
белый |
| Растворимость в воде: |
Растворим в воде (смешивается) и 80% уксусной кислоте (50 мг/мл). |
| Чувствительный: |
Hygroscopic |
| ИнЧИКей: |
DTERQYGMUDWYAZ-ZETCQYMHSA-N |
| Справочник по базе данных CAS: |
692-04-6(CAS DataBase Reference) |
| FDA UNII: |
470AD5VY1X |
N-EPSILON-ACETYL-L-LYSINE химические свойства, назначение, производство
Описание
Acetyllysine (or acetylated lysine) is an acetyl-derivative of the amino acid lysine. There are multiple forms of acetyllysine - this article refers to N-ε-acetyl-L-lysine. The other form is N-α-acetyl-Llysine.
In proteins, the acetylation of lysine residues is an important mechanism of epigenetics. It functions by regulating the binding of histones to DNA in nucleosomes and thereby controlling the expression of genes on that DNA. Non-histone proteins are acetylated as well. Unlike the functionally similar methyllysine, acetyllysine does not carry a positive charge on its side chain.
Histone acetyltransferases (HATs) catalyze the addition of acetyl groups from acetyl-CoA onto certain lysine residues of histones and non-histone proteins. Histone deacetylases (HDACs) catalyze the removal of acetyl groups from acetylated lysines.
Acetyllysine can be synthesized from lysine by the selective acetylation of the terminal amine group.
Химические свойства
white crystalline powder
Использование
N-Epsilon-acetyl-l-lysine is used in the metabolomics study on the combined effect of cocaine and ethanol via liquid chromatography-mass spectrometry metabolomics approach.
Определение
ChEBI: An N6-acyl-L-lysine where the N6-acyl group is specified as acetyl.
N-EPSILON-ACETYL-L-LYSINE препаратная продукция и сырье
сырьё
препарат
N-EPSILON-ACETYL-L-LYSINE поставщик
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