АЦЕТАРСОН
АЦЕТАРСОН атрибут
| Температура плавления: |
220.5°C |
| Температура кипения: |
72.17°C |
| плотность: |
1.0325 g/cm3(Temp: 15 °C) |
| температура хранения: |
Store at RT |
| растворимость: |
DMSO (Slightly), Methanol (Slightly, Heated, Sonicated) |
| форма: |
Твердый |
| пка: |
pKa 3.73 (H2O t=26) (Uncertain);7.9 (Uncertain); 9.3(H2O) (Uncertain) |
| цвет: |
Кристаллический материал |
| Мерк: |
13,53 |
| FDA UNII: |
806529YU1N |
| Код УВД: |
A07AX02,G01AB01,P01CD02 |
АЦЕТАРСОН химические свойства, назначение, производство
Использование
antiprotozoal; diethylamine salt as antiphilitic
Всемирная организация здравоохранения(ВОЗ)
Acetarsol, which has antiprotozoal and antitrichomonal activity,
has largely been discarded for systemic use because of its potential to cause
systemic poisoning. However, topical preparations for vaginal trichomoniasis are
still available and it is included in low concentrations (equal to or less than 0.45%)
in some medicated toothpastes.
Профиль безопасности
Poison by ingestion and intravenous routes. Human systemic effects by ingestion: respiratory system, endocrine system, dermatitis, and fever. Human systemic effects by intravagmal route: hallucinations, dlstorted perceptions, convulsions, nausea or vomiting, decreased urine volume, and fever. Mutation data reported. See also ARSENIC COMPOUNDS. When heated to decomposition it emits very toxic fumes of NOx, and As
Методы очистки
It crystallises from water in colourless prisms. It decomposes slowly on prolonged boiling in H2O or dilute alkalis. The N-propionyl derivative recrystallises from H2O with m 228-229o(dec). [Raiziss & Fisher J Am Chem Soc 48 1323 1926, Hewitt & King J Chem Soc 823 1926, Beilstein 16 I 491, 16 II 521, 16 III 1129.]
АЦЕТАРСОН препаратная продукция и сырье
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АЦЕТАРСОН поставщик
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