5-chloro-3-ethyl-1H-indole-2-carboxylic acid [2-(4-piperidin-1-yl-phenyl)-ethyl]-amide
5-chloro-3-ethyl-1H-indole-2-carboxylic acid [2-(4-piperidin-1-yl-phenyl)-ethyl]-amide атрибут
| Температура кипения: |
660.3±55.0 °C(Predicted) |
| плотность: |
1.218±0.06 g/cm3(Predicted) |
| температура хранения: |
2-8°C |
| растворимость: |
H2O: <2 мг/мл |
| форма: |
пудра |
| пка: |
14.87±0.30(Predicted) |
| цвет: |
белый |
| FDA UNII: |
7YW2S3Z2CB |
Заявления о рисках и безопасности
| Коды опасности |
Xn |
| Заявления о рисках |
22 |
| WGK Германия |
3 |
5-chloro-3-ethyl-1H-indole-2-carboxylic acid [2-(4-piperidin-1-yl-phenyl)-ethyl]-amide химические свойства, назначение, производство
Использование
Org 27569 is a drug that is a used in biological studies for structure-activity relationships of indole-carboxamides as CB1 receptor allosteric modulators.
Биологическая активность
Potent CB 1 receptor allosteric modulator (pEC 50 = 8.24). Significantly increases binding of the CB 1 agonist [ 3 H]CP 55.940 (pK b = 5.67) and decreases binding of the CB 1 inverse agonist [ 3 H]SR 141716A (pK b = 5.95). Inhibits CB 1 receptor antagonist efficacy in vitro (pK b = 7.57).
5-chloro-3-ethyl-1H-indole-2-carboxylic acid [2-(4-piperidin-1-yl-phenyl)-ethyl]-amide препаратная продукция и сырье
сырьё
препарат
5-chloro-3-ethyl-1H-indole-2-carboxylic acid [2-(4-piperidin-1-yl-phenyl)-ethyl]-amide поставщик
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