Этил метансульфона химические свойства, назначение, производство
Химические свойства
colourless liquid
Использование
Ethyl methanesulfonate is used as mutagen for both mammalian and plant cells. It finds application as a model alkylating agent in the study of deoxyribonucleic acid (DNA) repair processes.
Определение
ChEBI: A methanesulfonate ester resulting from the formal condensation of methanesulfonic acid with ethanol.
Общее описание
Clear colorless liquid. Denser than water.
Реакции воздуха и воды
Water soluble.
Профиль реактивности
Ethyl methanesulfonate alkylates nucleophiles such as hydroxy, amino and sulfhydryl groups in model and biological materials. Is hydrolyzed by excess aqueous alkali to non-corrosive and non-toxic products. Is hydrolyzed by water to a highly corrosive product .
Пожароопасность
Ethyl methanesulfonate is combustible.
Профиль безопасности
Confirmed carcinogen
with experimental carcinogenic,
neoplas tigenic, tumorigenic, and teratogenic
data. Poison by ingestion and intraperitoneal
routes. Experimental reproductive effects.
Human mutation data reported. When
heated to decomposition it emits toxic
fumes of SOx. See also SULFONATES and
ESTERS.
Возможный контакт
Used as a research tool for mutagenesis and carcinogenesis studies. Was considered as a possible
human male contraceptive. Also considered as a reversible
male hemosterilant for insects and mammalian pests.
Канцерогенность
Ethyl methanesulfonate is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.
Перевозки
UN2810 Toxic liquids, organic, n.o.s., Hazard
Class: 6.1; Labels: 6.1-Poisonous materials, Technical
Name Required. Military driver shall be given full and
complete information regarding shipment and conditions in
case of emergency. AR 50-6 deals specifically with the
shipment of chemical agents. Shipments of agent will be
escorted in accordance with AR 740-32.
Несовместимости
Vapors may form explosive mixture with
air. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep
away from alkaline materials, strong bases, strong acids,
oxoacids, and epoxides. Contact with moisture may cause
hydrolysis or other forms of decomposition
Этил метансульфона препаратная продукция и сырье
сырьё
препарат