3-фуранкарбоновой кислоты
3-фуранкарбоновой кислоты атрибут
| Температура плавления: |
120-122 °C (lit.) |
| Температура кипения: |
229.64°C |
| плотность: |
1.3220 |
| показатель преломления: |
1.4710 (estimate) |
| температура хранения: |
Sealed in dry,Room Temperature |
| растворимость: |
ДМСО (Мало растворим), метанол (Мало растворим) |
| форма: |
Твердый |
| пка: |
3.9(at 25℃) |
| цвет: |
От белого до бежевого |
| Растворимость в воде: |
нерастворимый |
| БРН: |
108638 |
| ИнЧИКей: |
IHCCAYCGZOLTEU-UHFFFAOYSA-N |
| LogP: |
1.030 |
| Справочник по базе данных CAS: |
488-93-7(CAS DataBase Reference) |
| FDA UNII: |
88A3S7RG98 |
| Справочник по химии NIST: |
3-Furancarboxylic acid(488-93-7) |
3-фуранкарбоновой кислоты химические свойства, назначение, производство
Описание
3-Furoic acid, also known as 3-carboxyfuran or 3-furoate, belongs to the class of organic compounds known as furoic acids. These are organic compounds containing a furoic acid moiety, with a structure characterized by a furan ring bearing a carboxylic acid group at the C2 or C3 carbon atom.
3-Furoic acid is an organic acid regularly occurring in urine of healthy individuals. It is used in synthesis of furan-2,5- and furan-2,4-dicarboxylic acid under solvent-free conditions via disproportionation reaction. It exhibits hypolipidemic activity in rodents. It lowers serum cholesterol and serum triglyceride levels in mice and rats.
Химические свойства
white to light yellow crystal powde
Использование
3-Furoic acid can be used as a reactant to synthesize:
Furan-2,5- and furan-2,4-dicarboxylic acid under solvent-free conditions via disproportionation reaction.
(±)-Hyperolactone A by reacting with 2-methylbutanal.
Furo[2,3-b]pyridin-4-one-5-carboxylate ester derivatives as potential non-nucleoside inhibitors of human herpesvirus polymerases.
Определение
ChEBI: A furoic acid carrying the carboxy group at position 3.
Биологическая активность
3-Furoic acid exhibits hypolipidemic activity in rodents. It lowers serum cholesterol and serum triglyceride levels in mice and rats.
Методы очистки
Crystallise the acid from water or aqueous EtOH, and sublime it in a vacuum. [Beilstein 18 I 439, 18 III/IV 4052, 18/6 V 196.]
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