thonzylamine hydrochloride химические свойства, назначение, производство
Химические свойства
White, crystalline powder; faint odor. Very soluble in water; freely soluble
in alcohol and chloroform; practically insoluble in
ether and benzene; pH 5.0–6.0 (2% solution).
Использование
Medicine (antihistamine).
Общее описание
Thonzylamine hydrochloride,2-[[2-(dimethylamino)-ethyl](p-methoxybenzyl)amino]pyrimidine hydrochloride, is a white crystallinepowder soluble in water (1:1), in alcohol (1:6), and in chloroform(1:4). A 2% aqueous solution has a pH of 5.5. It is similar in activity to tripelennamine but is claimed to be lesstoxic. The usual dose is 50 mg taken up to 4 times daily. Itis available in certain combination products.
Реакции воздуха и воды
Water soluble.
Профиль реактивности
thonzylamine hydrochloride behaves as a weak organic acid. Materials in this group are generally soluble in water. The resulting solutions contain moderate concentrations of hydrogen ions and have pH's of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible.
Угроза здоровью
SYMPTOMS: Symptoms of exposure to thonzylamine hydrochloride may include drowsiness, lethargy, fatigue, hypnosis, coma, vertigo, ataxia, tinnitus, blurred vision, tremors, anxiety, insomnia, excitement, hallucinations, delirium, convulsions, dry mouth, anorexia, nausea, vomiting, abdominal distress, constipation, diarrhea, central nervous system depression, gastrointestinal reactions, respiratory arrest and circulatory collapse.
Пожароопасность
Flash point data for thonzylamine hydrochloride are not available. thonzylamine hydrochloride is probably combustible.
thonzylamine hydrochloride препаратная продукция и сырье
сырьё
препарат