(2R,3R,4R,5S)-5-(4-benzaMido-2-oxopyriMidin-1(2H)-yl)-2-((benzoyloxy)Methyl)-4-fluoro-4-Methyltetrahydrofuran-3-yl benzoate

874638-94-5

CAS №: 874638-94-5

английское имя:: (2R,3R,4R,5S)-5-(4-benzaMido-2-oxopyriMidin-1(2H)-yl)-2-((benzoyloxy)Methyl)-4-fluoro-4-Methyltetrahydrofuran-3-yl benzoate

Синонимы:: Sofosbuvir imp-6;Sofosbuvir Impurity X;2'-epi-Sofosbuvir Desphosphate;Sofosbuvir Dibenzoyl Amino Impurity;(2R,3R,4R,5S)-5-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-2-((be...;(2R,3R,4R,5S)-5-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4-fluoro-4-methyltetrahydrofuran-3-yl benzoate;Benzamide, N-[1-[(2R)-3,5-di-O-benzoyl-2-deoxy-2-fluoro-2-methyl-α-D-erythro-pentofuranosyl]-1,2-dihydro-2-oxo-4-pyrimidinyl]-;N-[1-[(2R)-3,5-Di-O-benzoyl-2-deoxy-2-fluoro-2-methyl-alpha-D-erythro-pentofuranosyl]-1,2-dihydro-2-oxo-4-pyrimidinyl]benzamide;Sofosbuvir impurity 21/(2R,3R,4R,5S)-5-(4-benzaMido-2-oxopyriMidin-1(2H)-yl)-2-((benzoyloxy)Methyl)-4-fluoro-4-Methyltetrahydrofuran-3-yl benzoate

CBNumber:: CB72705027

Формула:: C31H26FN3O7

молекулярный вес:: 571.56

MOL File:: 874638-94-5.mol

атрибут

безопасность

использование

поставщик 45

продукт поиска:

(2R,3R,4R,5S)-5-(4-benzaMido-2-oxopyriMidin-1(2H)-yl)-2-((benzoyloxy)Methyl)-4-fluoro-4-Methyltetrahydrofuran-3-yl benzoate атрибут

Температура плавления:	174-175 °C(Solv: dichloromethane (75-09-2); hexane (110-54-3))
плотность:	1.34±0.1 g/cm3(Predicted)
пка:	8.51±0.20(Predicted)

Заявления о рисках и безопасности

(2R,3R,4R,5S)-5-(4-benzaMido-2-oxopyriMidin-1(2H)-yl)-2-((benzoyloxy)Methyl)-4-fluoro-4-Methyltetrahydrofuran-3-yl benzoate химические свойства, назначение, производство

Использование

2’-epi-Sofosbuvir Desphosphate is possible metabolite of Sofosbuvir (P839640) which is a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C.

(2R,3R,4R,5S)-5-(4-benzaMido-2-oxopyriMidin-1(2H)-yl)-2-((benzoyloxy)Methyl)-4-fluoro-4-Methyltetrahydrofuran-3-yl benzoate препаратная продукция и сырье

сырьё

препарат

(2R,3R,4R,5S)-5-(4-benzaMido-2-oxopyriMidin-1(2H)-yl)-2-((benzoyloxy)Methyl)-4-fluoro-4-Methyltetrahydrofuran-3-yl benzoate поставщик

Global( 45)Suppliers

поставщик	телефон	страна	номенклатура продукции	благоприятные условия
China National Standard Pharmaceutical Corporation Limited	+8615391658522	China	11927	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418684 +8618949823763	China	25363	58
BOC Sciences	16314854226; +16314854226	United States	19743	58
AFINE CHEMICALS LIMITED	+86-0571-85134551	China	15395	58
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	China	23556	58
Shenzhen Xingyue Biotechnology Co., Ltd	18124513697; 18124513697	China	1386	58
Nanjing XiZe Biotechnology CO., Ltd.	025-66023220 0086-15250997978	China	7787	55
Abydos Scientific	025-84767922 18936879710	China	1006	58
Shanghai Haohong Pharmaceutical Co., Ltd.	400-8210725 4008210725	China	40037	58
SHENZHEN PHYSTANDARD BIO-TECH CO.,LTD	0755-0755-0755-83725350 13380397412	China	10044	58

874638-94-5()подобный поиск:

Софосбувир 1,3,5-Три-O-бензоил-альфа-D-рибофураноза