BROMUCONAZOLE
BROMUCONAZOLE атрибут
| Температура плавления: |
84℃ |
| Температура кипения: |
504.3±60.0 °C(Predicted) |
| плотность: |
1.71 |
| давление пара: |
50 mg 1-1 |
| показатель преломления: |
1.6110 (estimate) |
| температура хранения: |
-20°C |
| растворимость: |
Chloroform (Slightly), Methanol (Slightly) |
| пка: |
2.75±0.10(Predicted) |
| БРН: |
8393967 |
| LogP: |
3.240 |
| Рейтинг продуктов питания EWG: |
1 |
| FDA UNII: |
PHS29ZMZ81 |
| Система регистрации веществ EPA: |
Bromuconazole (116255-48-2) |
| UNSPSC Code: |
41116107 |
| NACRES: |
NA.24 |
безопасность
- Заявления о рисках и безопасности
- код информации об опасности(GHS)
| Коды опасности |
Xn |
| Заявления о рисках |
22 |
| Заявления о безопасности |
36 |
| РИДАДР |
UN 3077 9 / PGIII |
| WGK Германия |
3 |
| RTECS |
XZ4130000 |
| Класс опасности |
6.1 |
| Группа упаковки |
III |
| Банк данных об опасных веществах |
116255-48-2(Hazardous Substances Data) |
| Токсичность |
LD50 orally in rats, mice: 365, 1151 mg/kg; LD50 dermally in rats: >2000 mg/kg; LD50 by inhalation in rabbits: >5 mg/l; LC50(96 hr) in rainbow trout, bluegill sunfish (mg/l): 1.7, 3.1 (Pepin) |
| символ（GHS） |
 
|
| сигнальное слово |
Warning |
| Заявление об опасности |
| пароль |
Заявление об опасности |
Класс опасности |
категория |
сигнальное слово |
пиктограмма |
предупреждение |
| H302 |
Вредно при проглатывании. |
Острая токсичность, пероральная |
Категория 4 |
Предупреждение |
|
P264, P270, P301+P312, P330, P501 |
| H400 |
Чрезвычайно токсично для водных организмов. |
Опасность для водной среды, острая опасность |
Категория 1 |
Предупреждение |
|
P273, P391, P501 |
|
| Внимание |
| P273 |
Избегать попадания в окружающую среду. |
| P301+P312+P330 |
ПРИ ПРОГЛАТЫВАНИИ: Обратиться за медицинской помощью
при плохом самочувствии. Прополоскать рот. |
|
BROMUCONAZOLE химические свойства, назначение, производство
Использование
Bromuconazole is used on winter wheat and barley for the control
of foliar mildews, rusts and other diseases.
Определение
ChEBI: A member of the class of oxolanes carrying 1,2,4-triazol-ylmethyl and 2,4-dichlorophenyl substituents at position 2 as well as a bromo substituent at position 4. A foliar applied conazole fungicide for a range of crops including cereals, fruit, vegetables
and vines.
Метаболический путь
Bromuconazole is a relatively stable compound which is not readily
hydrolysed, is quite persistent in soil and is subject to relatively slow
photodegradation. It is metabolised in plants but the parent compound
tends to be the major residue. However, bromuconazole is almost completely
metabolised in animals and birds (chickens) and its metabolites
are rapidly eliminated.
As with many other triazole fungicides, metabolism is very complex.
Bromuconazole exists in four forms (two diastereoisomeric pairs). There
are numerous sites available for biotransformation (lack of regioselectivity)
and there is also a lack of stereoselectivity at most sites. For example,
there are also four forms of metabolite 5 (4-hydroxybromuconazole) (two
diastereoisomeric pairs as with bromuconazole itself). Oxidation of
secondary alcohols to ketones and the thiolation of certain sites further
complicate the picture. Thiolation presumably occurs via the involvement
of glutathione but mercapturic acid conjugates (N-acetylcysteines)
do not appear to have been isolated.
Bromuconazole has been the subject of an evaluation by the Pesticide
Safety Directorate of UK MAFF. All of the information presented below is
derived from this source (PSD, 1996). All reported radiolabelled studies
were conducted using [14C-phenyl]bromuconazole.
BROMUCONAZOLE препаратная продукция и сырье
сырьё
препарат
BROMUCONAZOLE поставщик
Global( 65)Suppliers
116255-48-2()подобный поиск: