Y 134 химические свойства, назначение, производство
Использование
Y 134 is a SERM displaying selectivity for ERα over ERβ.
Биологическая активность
Selective estrogen receptor modulator (SERM) that displays selectivity for ER α over ER β (K i values are 0.09 and 11.31 nM respectively) and no cross-reactivity with mineralocorticoid, glucocorticoid, androgen and progesterone receptors. Acts as an agonist in the bone and antagonist in reproductive tissue. Suppresses estrogen-stimulated proliferation of ER-positive human breast cancer MCF-7 and T47D cells.
Y 134 препаратная продукция и сырье
сырьё
препарат