Гемиглиптин

911637-19-9

CAS №: 911637-19-9

Химическое название:: Гемиглиптин

английское имя:: GeMigliptin

Синонимы:: LC15-0444;GeMigliptin;GeMigliptin WS;Gemigliptin - G10587;GeMigliptin Tartarate;Gemigliptin Hydrochloride;Product name:-Gemigliptintartarate;Inhibitor,DPP,Gemigliptin,Dipeptidyl Peptidase,inhibit;(S)-1-(2-Amino-4-(2,4-bis(trifluoromethyl)-5,6-dihydropyrido[3,4-d]pyrimidin-7(8H)-yl)-4-oxobutyl)-5,5-difluoropiperidin-2-one;1-[(2S)-2-amino-4-[2,4-bis(trifluoromethyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-7-yl]-4-oxobutyl]-5,5-difluoropiperidin-2-one

CBNumber:: CB82627898

Формула:: C18H19F8N5O2

молекулярный вес:: 489.36

MOL File:: 911637-19-9.mol

атрибут

безопасность

использование

поставщик 42

продукт поиска:

Гемиглиптин атрибут

Температура кипения:	539.1±50.0 °C(Predicted)
плотность:	1.54±0.1 g/cm3(Predicted)
температура хранения:	Store at -20°C
растворимость:	DMSO:74.0(Max Conc. mg/mL);151.21(Max Conc. mM) Ethanol:7.0(Max Conc. mg/mL);14.3(Max Conc. mM) Water:12.0(Max Conc. mg/mL);24.52(Max Conc. mM)
форма:	Solid
пка:	7.33±0.10(Predicted)
цвет:	White to orange
FDA UNII:	5DHU18M5D6
Словарь наркотиков NCI:	gemigliptin
Код УВД:	A10BH06

Заявления о рисках и безопасности

Гемиглиптин химические свойства, назначение, производство

Описание

Gemigliptin is a prolyl-specific dipeptidyl aminopeptidase IV (DPP IV, DPP-4, CD26) inhibitor approved for the treatment of type 2 diabetes mellitus by the Korean Food and Drug Administration in 2012. Gemigliptin was discovered and developed by LG Life Sciences and is now the sixth DPP-4 inhibitor approved for the treatment of type 2 diabetes. At the time this review was prepared, there were no publications describing the discovery strategy and preclinical data that led to the advancement of gemigliptin to the clinic.

Использование

Gemigliptin Hydrochloride is used in biological studies as a novel dipeptidyl peptidase IV (DPP-IV) inhibitors and potential antidiabetic drug.

Гемиглиптин препаратная продукция и сырье

сырьё

препарат

Гемиглиптин поставщик

Global( 42)Suppliers

поставщик	телефон	страна	номенклатура продукции	благоприятные условия
Amadis Chemical Company Limited	571-89925085	China	131980	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+undefined18621343501	China	33350	58
LEAPCHEM CO., LTD.	+86-852-30606658	China	43348	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	China	8474	58
Aceschem Inc.	+1-817863-6948 +1-（817）863-6948	United States	19639	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	China	11681	58
TargetMol Chemicals Inc.	+1-781-999-5354	United States	19973	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418684 +8618949823763	China	25363	58
Senova Technology Co. Ltd.	+86-0755-86703119 +8618503098836	China	351	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	China	21667	55

911637-19-9(Гемиглиптин)подобный поиск:

Трелаглиптин