Флупреднизолон химические свойства, назначение, производство
Описание
Fluprednisolone (6α-fluoro-11β,17,21-trihydroxy-pregna-1,4-diene-3,20-dione) is the 16-desmethyl analogue of
paramethasone. Its activity is similar to that of paramethasone, and it has approximately 2.5 times the
antirheumatic potency of prednisolone. With doses of 2 to 7 mg, evidence of salt and water retention has not
been noted. The therapeutic index, however, probably is the same or only a little greater than that for
prednisolone. Because no new adverse reactions have been noted during the administration of this drug on a
short-term basis, it seems that a 6α-fluoro group does not deleteriously affect the activity of prednisolone
(49,75).
Использование
6α-Fluprednisolone is an anti-inflammatory corticosteroid metabolite.
Флупреднизолон препаратная продукция и сырье
сырьё
Кислота серная
Кислота уксусная
Натрий бикарбонат
Pregn-4-ene-3,20-dione,21-(acetyloxy)-6-fluoro-11,17-dihydroxy-, (6a,11b)- (9CI)
Pregn-4-ene-3,20-dione, 6β-fluoro-11β,17,21-trihydroxy-, 21-acetate (7CI,8CI)
препарат