Dinoprost tromethamine
Dinoprost tromethamine атрибут
| Температура плавления: |
100-101° |
| температура хранения: |
-20°C |
| растворимость: |
H2O: 1 мг/мл. Водные растворы стабильны в течение 30 дней при температуре 2–8°C и в течение нескольких месяцев в замороженном виде при температуре использовать аликвоты. Избегайте повторяющихся циклов замораживания/оттаивания. |
| форма: |
пудра |
| цвет: |
белый |
| Биологические источники: |
synthetic |
| Растворимость в воде: |
H2O: 1mg/mL
ethanol: 50mg/mL |
| Мерк: |
13,7970 |
| БРН: |
4087514 |
| Стабильность:: |
гигроскопичный |
| ИнЧИКей: |
IYGXEHDCSOYNKY-RZHHZEQLSA-N |
| FDA UNII: |
CT6BBQ5A68 |
| Словарь наркотиков NCI: |
dinoprost tromethamine |
| UNSPSC Code: |
12352401 |
| NACRES: |
NA.77 |
Dinoprost tromethamine химические свойства, назначение, производство
Описание
Dinoprost tromethamine is a synthetic analogue of prostaglandin. F2α is an autocrine hormone present in many mammalian tissues. It is used to cause luteolysis in the cow, sow and mare. It is given as a single injection by im or sc routes, the recommended dosage rate is 25 mg cow; 10 mg sow and 5 mg mare. It is rapidly absorbed from the injection site. It has an extremely short half life of only a few minutes, it is almost completely cleared following one or two passages through the liver and/or lungs.
Химические свойства
White Solid
Определение
dinoprost tromethamine is a synthetic analogue of the naturally occurring prostaglandin F2 alpha. Prostaglandin F2 alpha stimulates myometrial activity, relaxes the cervix, inhibits corpus luteal steroidogenesis, and induces luteolysis by direct action on the corpus luteum.
Показания
Dinoprost tromethamine salt (Prostaglandin F2α tromethamine salt) is an orally active, potent prostaglandin F (PGF) receptor (FP receptor) agonist. Dinoprost tromethamine salt is a luteolytic hormone produced locally in the endometrial luminal epithelium and corpus luteum (CL). Dinoprost tromethamine salt plays a key role in the onset and progression of labour.
Профиль безопасности
Poison by intraperitoneal, subcutaneous, intravenous, and intramuscular routes. Moderately toxic by ingestion. Human reproductive effects by intervagmal route: terminates pregnancy, effects on fertility. Experimental teratogenic and reproductive effects. When heated to
decomposition it emits toxic fumes of NOx. See also other prostaglandin entries.
Dinoprost tromethamine препаратная продукция и сырье
сырьё
препарат
Dinoprost tromethamine поставщик
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