Methyl 2-methoxy-5-sulfamoylbenzoate
Methyl 2-methoxy-5-sulfamoylbenzoate атрибут
| Температура плавления: |
175-177 °C (lit.) |
| Температура кипения: |
439.8±55.0 °C(Predicted) |
| плотность: |
1.360±0.06 g/cm3(Predicted) |
| температура хранения: |
2-8°C |
| растворимость: |
ДМСО (Мало растворим), метанол (Мало растворим) |
| пка: |
9.94±0.60(Predicted) |
| цвет: |
От белого до не совсем белого |
| LogP: |
0.36 |
| Справочник по базе данных CAS: |
33045-52-2(CAS DataBase Reference) |
| FDA UNII: |
F8XVA6KYT6 |
Methyl 2-methoxy-5-sulfamoylbenzoate химические свойства, назначение, производство
Использование
Methyl 2-methoxy-5-sulfamoylbenzoate is a reactant used in the preparation of many pharmaceutical compounds used as anticoagulants, HCV NS5B polymerase inhibitors, therapeutic drugs for treatment of neurodegenerative diseases and oral hypog lycemic agents.
Подготовка
Methyl 2-methoxy-5-aminosulfonyl benzoate is an important intermediate for the synthesis of sulpiride, which is the main drug for treatment of psychiatric disorders such as schizophrenia and depression. The synthetic route of methyl 2-methoxy-5-aminosulfonyl benzoate is composed mainly of etherification (phenol hydroxyl), sulfonyl chloride, amination and esterification, which prepared successfully with the help of salicylic acid and methyl salicylate as precursor. The raw materials of the synthetic route are salicylic acid and methyl salicylate, which was synthesized by etherification (phenol hydroxyl), sulfonyl chloride, amination and esterification.
synthetic procedure of Methyl 2-Methoxy-5-Aminosulfonyl Benzoate
Общее описание
Methyl 2-methoxy-5-sulfamoylbenzoate is also referred to as 2-methoxy-5-sulfamoyl methyl benzoate or methyl 5-(aminosulphonyl)-2-methoxybenzoate.
Methyl 2-methoxy-5-sulfamoylbenzoate препаратная продукция и сырье
сырьё
препарат
Methyl 2-methoxy-5-sulfamoylbenzoate поставщик
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