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ChemicalBook >> CAS DataBase List >> Abemaciclib mesylate (LY2835219)

Abemaciclib mesylate (LY2835219)

Abemaciclib mesylate (LY2835219) price.
  • $44 - $2250
  • Product name: Abemaciclib mesylate (LY2835219)
  • CAS: 1231930-82-7
  • MF: C28H36F2N8O3S
  • MW: 602.71
  • EINECS:
  • MDL Number:MFCD25562906
  • Synonyms:2-Pyrimidinamine, N-[5-[(4-ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-, methanesulfonate (1:1);N-[5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-2-pyrimidinamine methanesulfonate (1:1) LY2835219;LY2835219 mesylate;Bemaciclib(salt);N-[5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl]-5-fluoro-4-(7-fluoro-2-methyl-3-propan-2-ylbenzimidazol-5-yl)pyrimidin-2-amine,methanesulfonic acid;N-(5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine methanesulfonate;N-[5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methyle;LY2835219 Ms salt, Abemaciclib Ms salt
Price21 Properties Safety Information Description
21 prices
Selected condition：
Brand
  • Adipogen Life Sciences
  • AK Scientific
  • Arctom
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • TRC
Package
  • 1mg
  • 2.5mg
  • 5mg
  • 10mg
  • 20mg
  • 50mg
  • 100mg
  • 200mg
  • 250mg
  • 500mg
  • 1g
  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-L0303-M100
  • Product descriptionLY2835219 ≥99%
  • Packaging100mg
  • Price$176
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2528AH
  • Product descriptionBemaciclib
  • Packaging250mg
  • Price$331
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60276
  • Product descriptionAbemaciclibMesylate(LY2835219) ≥98%
  • Packaging20mg
  • Price$208
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA159696
  • Product descriptionAbemaciclib mesylate
  • Packaging10mg
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number17740
  • Product descriptionLY2835219 (methanesulfonate) ≥95%
  • Packaging1mg
  • Price$44
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17740
  • Product descriptionLY2835219 (methanesulfonate) ≥95%
  • Packaging5mg
  • Price$63
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17740
  • Product descriptionLY2835219 (methanesulfonate) ≥95%
  • Packaging10mg
  • Price$93
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM158972
  • Product descriptionN-(5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-aminemethanesulfonate 98%
  • Packaging250mg
  • Price$314
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1229
  • Product descriptionAbemaciclib(methanesulfonate) 99.95%
  • Packaging5mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1229
  • Product descriptionAbemaciclib(methanesulfonate) 99.95%
  • Packaging10mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1229
  • Product descriptionAbemaciclib(methanesulfonate) 99.95%
  • Packaging50mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1229
  • Product descriptionAbemaciclib(methanesulfonate) 99.95%
  • Packaging100mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1229
  • Product descriptionAbemaciclib(methanesulfonate) 99.95%
  • Packaging200mg
  • Price$190
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1229
  • Product descriptionAbemaciclib(methanesulfonate) 99.95%
  • Packaging500mg
  • Price$350
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004169
  • Product descriptionLY2835219 98+%
  • Packaging50mg
  • Price$358
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004169
  • Product descriptionLY2835219 98+%
  • Packaging100mg
  • Price$461
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences CDX-L0303-M100 LY2835219 ≥99% 100mg $176 2021-12-16 Buy
AK Scientific 2528AH Bemaciclib 250mg $331 2021-12-16 Buy
Arctom CFN60276 AbemaciclibMesylate(LY2835219) ≥98% 20mg $208 2021-12-16 Buy
Biosynth Carbosynth FA159696 Abemaciclib mesylate 10mg $75 2021-12-16 Buy
Cayman Chemical 17740 LY2835219 (methanesulfonate) ≥95% 1mg $44 2024-03-01 Buy
Cayman Chemical 17740 LY2835219 (methanesulfonate) ≥95% 5mg $63 2024-03-01 Buy
Cayman Chemical 17740 LY2835219 (methanesulfonate) ≥95% 10mg $93 2024-03-01 Buy
Chemenu CM158972 N-(5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-aminemethanesulfonate 98% 250mg $314 2021-12-16 Buy
ChemScene CS-1229 Abemaciclib(methanesulfonate) 99.95% 5mg $60 2021-12-16 Buy
ChemScene CS-1229 Abemaciclib(methanesulfonate) 99.95% 10mg $90 2021-12-16 Buy
ChemScene CS-1229 Abemaciclib(methanesulfonate) 99.95% 50mg $120 2021-12-16 Buy
ChemScene CS-1229 Abemaciclib(methanesulfonate) 99.95% 100mg $150 2021-12-16 Buy
ChemScene CS-1229 Abemaciclib(methanesulfonate) 99.95% 200mg $190 2021-12-16 Buy
ChemScene CS-1229 Abemaciclib(methanesulfonate) 99.95% 500mg $350 2021-12-16 Buy
Crysdot CD31004169 LY2835219 98+% 50mg $358 2021-12-16 Buy
Crysdot CD31004169 LY2835219 98+% 100mg $461 2021-12-16 Buy
Next Last

Properties

storage temp. :-20°
solubility :Soluble in DMSO (up to at least 25 mg/ml) or in Water (up to at least 25 mg/ml).
form :solid
color :Off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
CAS DataBase Reference :1231930-82-7

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

LY2835219 is an orally-bioavailable dual inhibitor of cyclin-dependent kinase 4 (CDK4) and CDK6 (IC50s = 2 and 10 nM, respectively). Through this mechanism, it blocks phosphorylation of retinoblastoma protein, resulting in arrest of cell cycling in the G1 phase. LY2835219 has antitumor action against xenografts when used alone or in combination with other chemotherapeutic compounds.

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Suppliers and manufacturers

career henan chemical co
LY2835219
$7.00 /1KG
LY2835219 CAS:1231930-82-7
TargetMol Chemicals Inc.
Abemaciclib methanesulfonate
$30.00 /2mg
Abemaciclib methanesulfonate CAS:1231930-82-7
Capot Chemical Co.,Ltd.
Beijing Cooperate Pharmaceutical Co.,Ltd
ATK CHEMICAL COMPANY LIMITED
Biochempartner
Hubei Jusheng Technology Co.,Ltd.
BOC Sciences
Chongqing Chemdad Co., Ltd
Shenzhen Excellent Biotech Co., Ltd.