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ChemicalBook >> CAS DataBase List >> 2-AMino-6-chloro-α-cyano-3-(ethoxycarbonyl)-4H-1-benzopyran-4-acetic Acid Ethyl Ester

2-AMino-6-chloro-α-cyano-3-(ethoxycarbonyl)-4H-1-benzopyran-4-acetic Acid Ethyl Ester

2-AMino-6-chloro-α-cyano-3-(ethoxycarbonyl)-4H-1-benzopyran-4-acetic Acid Ethyl Ester price.
  • $8 - $1400
  • Product name: 2-AMino-6-chloro-α-cyano-3-(ethoxycarbonyl)-4H-1-benzopyran-4-acetic Acid Ethyl Ester
  • CAS: 305834-79-1
  • MF: C17H17ClN2O5
  • MW: 364.78
  • EINECS:
  • MDL Number:MFCD02681303
  • Synonyms:2-AMino-6-chloro-α-cyano-3-(ethoxycarbonyl)-4H-1-benzopyran-4-acetic Acid Ethyl Ester;2-Amino-6-chloro-alpha-cyano-3-(ethoxycarbonyl)-4H-1-benzopyran-4-acetic acid ethyl ester;Akt Activator II, SC79 ;Akt Activator II;SC79;SC 79;AKT ACTIVATOR II;4H-1-Benzopyran-4-acetic acid, 2-amino-6-chloro-α-cyano-3-(ethoxycarbonyl)-, ethyl ester;SC79;SC 79;Akt Activator II, SC79 - CAS 305834-79-1 - Calbiochem
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  • AK Scientific
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  • Axon Medchem
  • Biorbyt Ltd
  • Cayman Chemical
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  • ManufacturerAK Scientific
  • Product number1749CJ
  • Product descriptionEthyl2-amino-6-chloro-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate
  • Packaging10mg
  • Price$216
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA261312
  • Product descriptionEthyl2-amino-6-chloro-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate 98+%
  • Packaging1mg
  • Price$8
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA261312
  • Product descriptionEthyl2-amino-6-chloro-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate 98+%
  • Packaging5mg
  • Price$13
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA261312
  • Product descriptionEthyl2-amino-6-chloro-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate 98+%
  • Packaging10mg
  • Price$17
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA261312
  • Product descriptionEthyl2-amino-6-chloro-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate 98+%
  • Packaging25mg
  • Price$24
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA261312
  • Product descriptionEthyl2-amino-6-chloro-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate 98+%
  • Packaging50mg
  • Price$31
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA261312
  • Product descriptionEthyl2-amino-6-chloro-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate 98+%
  • Packaging100mg
  • Price$54
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA261312
  • Product descriptionEthyl2-amino-6-chloro-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate 98+%
  • Packaging250mg
  • Price$106
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA261312
  • Product descriptionEthyl2-amino-6-chloro-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate 98+%
  • Packaging1g
  • Price$277
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB5663
  • Product descriptionSC79
  • Packaging10mg
  • Price$85
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB5663
  • Product descriptionSC79
  • Packaging50mg
  • Price$245
  • Updated2021-12-16
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  • ManufacturerAxon Medchem
  • Product numberAxon2507
  • Product descriptionSC79 98%
  • Packaging5mg
  • Price$82.5
  • Updated2021-12-16
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  • ManufacturerAxon Medchem
  • Product numberAxon2507
  • Product descriptionSC79 98%
  • Packaging2x5mg
  • Price$132
  • Updated2021-12-16
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  • ManufacturerAxon Medchem
  • Product numberAxon2507
  • Product descriptionSC79 98%
  • Packaging25mg
  • Price$291.5
  • Updated2021-12-16
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  • ManufacturerAxon Medchem
  • Product numberAxon2507
  • Product descriptionSC79 98%
  • Packaging2x25mg
  • Price$462
  • Updated2021-12-16
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  • ManufacturerBiorbyt Ltd
  • Product numberorb545909
  • Product descriptionSC-79 >98%
  • Packaging5mg
  • Price$154.7
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1749CJ Ethyl2-amino-6-chloro-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate 10mg $216 2021-12-16 Buy
Ambeed A261312 Ethyl2-amino-6-chloro-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate 98+% 1mg $8 2021-12-16 Buy
Ambeed A261312 Ethyl2-amino-6-chloro-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate 98+% 5mg $13 2021-12-16 Buy
Ambeed A261312 Ethyl2-amino-6-chloro-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate 98+% 10mg $17 2021-12-16 Buy
Ambeed A261312 Ethyl2-amino-6-chloro-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate 98+% 25mg $24 2021-12-16 Buy
Ambeed A261312 Ethyl2-amino-6-chloro-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate 98+% 50mg $31 2021-12-16 Buy
Ambeed A261312 Ethyl2-amino-6-chloro-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate 98+% 100mg $54 2021-12-16 Buy
Ambeed A261312 Ethyl2-amino-6-chloro-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate 98+% 250mg $106 2021-12-16 Buy
Ambeed A261312 Ethyl2-amino-6-chloro-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate 98+% 1g $277 2021-12-16 Buy
ApexBio Technology B5663 SC79 10mg $85 2021-12-16 Buy
ApexBio Technology B5663 SC79 50mg $245 2021-12-16 Buy
Axon Medchem Axon2507 SC79 98% 5mg $82.5 2021-12-16 Buy
Axon Medchem Axon2507 SC79 98% 2x5mg $132 2021-12-16 Buy
Axon Medchem Axon2507 SC79 98% 25mg $291.5 2021-12-16 Buy
Axon Medchem Axon2507 SC79 98% 2x25mg $462 2021-12-16 Buy
Biorbyt Ltd orb545909 SC-79 >98% 5mg $154.7 2021-12-16 Buy

Properties

Boiling point :524.8±50.0 °C(Predicted)
Density :1.340±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: soluble20mg/mL, clear
pka :3.03±0.40(Predicted)
form :powder
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

Description

SC-79 is an activator of Akt that blocks its membrane translocation while allowing its phosphorylation, in the cytosol, by upstream kinases. For example, both Thr308 and Ser473 on Akt are phosphorylated in serum starved HeLa cells treated for 1 hour with insulin growth factor and SC-79 (4 μg/ml). SC-79 permits phosphorylation and activation of all isoforms of Akt, it is active in multiple cell types, and works in both receptor tyrosine kinase- and G protein-coupled receptor-mediated signaling. SC-79 has been used to elucidate the role of Akt signaling in neuronal survival, glucose-mediated apoptosis in podocytes, and miR-221-regulated cancer cell proliferation.

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