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ChemicalBook >> CAS DataBase List >> (+)-ALPHA-DIHYDROTETRABENAZINE

(+)-ALPHA-DIHYDROTETRABENAZINE

(+)-ALPHA-DIHYDROTETRABENAZINE price.
  • $121 - $2375
  • Product name: (+)-ALPHA-DIHYDROTETRABENAZINE
  • CAS: 3466-75-9
  • MF: C19H29NO3
  • MW: 319.44
  • EINECS:
  • MDL Number:MFCD20275194
  • Synonyms:(+)-ALPHA-DIHYDROTETRABENAZINE;2H-BENZO[A]QUINOLIZINE-2-OL, 1,3,4,6,7,11B-HEXAHYDRO-3-ISOBUTYL-9,10-DIMETHOXY-;DIHYDROTETRABENAZINE;DTBZ;2H-Benzo[a]quinolizin-2-ol, 1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-;1,3,4,6,7,11b-Hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-ol;(+)-ALPHA-DIHYDROTETRABEZINE;Hydroxy Tetrabenazine
5 prices
Selected condition:
Brand
  • AK Scientific
  • Cayman Chemical
  • Chemtos
  • TRC
Package
  • 500μg
  • 1mg
  • 10mg
  • 100mg
  • ManufacturerAK Scientific
  • Product numberZ3455
  • Product descriptiontrans-Dihydrotetrabenazine
  • Packaging1mg
  • Price$353
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number27182
  • Product descriptionDihydrotetrabenazine
  • Packaging500μg
  • Price$121
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number27182
  • Product descriptionDihydrotetrabenazine
  • Packaging1mg
  • Price$230
  • Updated2024-03-01
  • Buy
  • ManufacturerChemtos
  • Product numberT-6836
  • Product description2-alpha-DihydrotetrabenazineLabeledd7
  • Packaging10mg
  • Price$2375
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberH627630
  • Product descriptionHydroxyTetrabenazine-MixtureofcisandtransIsomers
  • Packaging100mg
  • Price$175
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific Z3455 trans-Dihydrotetrabenazine 1mg $353 2021-12-16 Buy
Cayman Chemical 27182 Dihydrotetrabenazine 500μg $121 2024-03-01 Buy
Cayman Chemical 27182 Dihydrotetrabenazine 1mg $230 2024-03-01 Buy
Chemtos T-6836 2-alpha-DihydrotetrabenazineLabeledd7 10mg $2375 2021-12-16 Buy
TRC H627630 HydroxyTetrabenazine-MixtureofcisandtransIsomers 100mg $175 2021-12-16 Buy

Properties

Boiling point :457.8±45.0 °C(Predicted)
Density :1.13±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Chloroform: soluble; Methanol: soluble
form :A solid
pka :14.75±0.40(Predicted)
CAS DataBase Reference :3466-75-9

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

Dihydrotetrabenazine is an active metabolite of the vesicular monoamine transporter 2 (VMAT2) inhibitor tetrabenazine that is generated by hepatic carbonyl reductases. Dihydrotetrabenazine binds to mouse pons medulla, hypothalamus, and striatum (Kds = 2.72, 2.28, and 2.4 nM, respectively) and inhibits synaptic vesicular serotonin (5-HT) uptake (IC50s = 2.2, 2.8, and 2.3 nM, respectively). It also binds to human caudate nucleus, hippocampus, and substantia nigra pars compacta (Kds = 2.9, 2.5, and 2.8 nM, respectively). Dihydrotetrabenazine stereoisomers bind to VMAT2 in rat striatum.

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