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ChemicalBook >> CAS DataBase List >> EO 1428

EO 1428

EO 1428 price.
  • $44 - $1385
  • Product name: EO 1428
  • CAS: 321351-00-2
  • MF: C20H16BrClN2O
  • MW: 415.71
  • EINECS:
  • MDL Number:MFCD11100188
  • Synonyms:p38 MAP Kinase Inhibitor VIII;EO 1428;(2-Methylphenyl)-[4-[(2-amino-4-bromophenyl)amino]-2-chlorophenyl]methanone;p38 MAPK Inhibitor VIII;Methanone, [4-[(2-amino-4-bromophenyl)amino]-2-chlorophenyl](2-methylphenyl)-
11 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 50
  • 1mg
  • 2.5mg
  • 5MG
  • 10mg
  • 50mg
  • ManufacturerAK Scientific
  • Product number3107CR
  • Product description(4-((2-Amino-4-bromophenyl)amino)-2-chlorophenyl)(2-methylphenyl)methanone
  • Packaging1mg
  • Price$147
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0001223
  • Product descriptionEO 1428 95.00%
  • Packaging5MG
  • Price$500.02
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7215
  • Product descriptionEO1428
  • Packaging10mg
  • Price$339
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7215
  • Product descriptionEO1428
  • Packaging50mg
  • Price$1385
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number21229
  • Product descriptionp38 MAPK Inhibitor VIII ≥98%
  • Packaging1mg
  • Price$44
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21229
  • Product descriptionp38 MAPK Inhibitor VIII ≥98%
  • Packaging5mg
  • Price$118
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21229
  • Product descriptionp38 MAPK Inhibitor VIII ≥98%
  • Packaging10mg
  • Price$214
  • Updated2024-03-01
  • Buy
  • ManufacturerTocris
  • Product number2908
  • Product descriptionEO1428 ≥98%(HPLC)
  • Packaging10
  • Price$225
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number2908
  • Product descriptionEO1428 ≥98%(HPLC)
  • Packaging50
  • Price$915
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberE888148
  • Product descriptionEO1428
  • Packaging2.5mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number255251
  • Product descriptionEO 1428
  • Packaging10mg
  • Price$480
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3107CR (4-((2-Amino-4-bromophenyl)amino)-2-chlorophenyl)(2-methylphenyl)methanone 1mg $147 2021-12-16 Buy
American Custom Chemicals Corporation INB0001223 EO 1428 95.00% 5MG $500.02 2021-12-16 Buy
ApexBio Technology B7215 EO1428 10mg $339 2021-12-16 Buy
ApexBio Technology B7215 EO1428 50mg $1385 2021-12-16 Buy
Cayman Chemical 21229 p38 MAPK Inhibitor VIII ≥98% 1mg $44 2024-03-01 Buy
Cayman Chemical 21229 p38 MAPK Inhibitor VIII ≥98% 5mg $118 2024-03-01 Buy
Cayman Chemical 21229 p38 MAPK Inhibitor VIII ≥98% 10mg $214 2024-03-01 Buy
Tocris 2908 EO1428 ≥98%(HPLC) 10 $225 2021-12-16 Buy
Tocris 2908 EO1428 ≥98%(HPLC) 50 $915 2021-12-16 Buy
TRC E888148 EO1428 2.5mg $250 2021-12-16 Buy
Usbiological 255251 EO 1428 10mg $480 2021-12-16 Buy

Properties

storage temp. :Store at +4°C
solubility :Soluble to 100 mM in DMSO and to 50 mM in ethanol
form :Powder

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

p38 MAP Kinase Inhibitor VIII is a synthetic 4-aminobenzophenone small molecule identified in an optimization study for inhibitors of p38 MAP kinase. p38 MAP Kinase Inhibitor VIII is described to inhibit the p38α and p38β isoforms of the kinase by occupying the ATP-binding cleft. This inhibition is described to potently block the release of TNF-α (IC50 = 5 nM) and the proinflammatory interleukins IL-1β, IL-6, IL-8, and IL-10 (IC50s = 30, 17, 4, 74 nM).

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