Gefitinib-d6
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- $130 - $3520
- Product name: Gefitinib-d6
- CAS: 1228664-49-0
- MF: C22H24ClFN4O3
- MW: 446.91
- EINECS:
- MDL Number:MFCD21363632
- Synonyms:Gefitinib-d6;Hexadeuterated gefitinib;[2H6]-Gefitinib;N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy-1,1,2,2,3,3-d6]-4-quinazolinamine
6 prices
Selected condition：
Brand
- AK Scientific
- Cayman Chemical
- Medical Isotopes, Inc.
- TRC
Package
- 500μg
- 1mg
- 10mg
- 25mg
- ManufacturerAK Scientific
- Product number3663DG
- Product descriptionGefitinib-d6
- Packaging1mg
- Price$370
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number22364
- Product descriptionGefitinib-d6 ≥99% deuterated forms (d1-d6)
- Packaging500μg
- Price$130
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number22364
- Product descriptionGefitinib-d6 ≥99% deuterated forms (d1-d6)
- Packaging1mg
- Price$243
- Updated2024-03-01
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product numberD74920
- Product descriptionGefitinib-d6
- Packaging1mg
- Price$490
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberG304008
- Product descriptionGefitinib-d6
- Packaging10mg
- Price$1540
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberG304008
- Product descriptionGefitinib-d6
- Packaging25mg
- Price$3520
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 3663DG | Gefitinib-d6 | 1mg | $370 | 2021-12-16 | Buy |
| Cayman Chemical | 22364 | Gefitinib-d6 ≥99% deuterated forms (d1-d6) | 500μg | $130 | 2024-03-01 | Buy |
| Cayman Chemical | 22364 | Gefitinib-d6 ≥99% deuterated forms (d1-d6) | 1mg | $243 | 2024-03-01 | Buy |
| Medical Isotopes, Inc. | D74920 | Gefitinib-d6 | 1mg | $490 | 2021-12-16 | Buy |
| TRC | G304008 | Gefitinib-d6 | 10mg | $1540 | 2021-12-16 | Buy |
| TRC | G304008 | Gefitinib-d6 | 25mg | $3520 | 2021-12-16 | Buy |
Properties
storage temp. :Store at -20°C
solubility :DMF: 20 mg/ml,DMSO: 20 mg/ml,DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml,Ethanol: 0.3 mg/ml
form :A solid
color :White to off-white
solubility :DMF: 20 mg/ml,DMSO: 20 mg/ml,DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml,Ethanol: 0.3 mg/ml
form :A solid
color :White to off-white
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||||
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Description
Gefitinib-d6 is intended for use as an internal standard for the quantification of gefitinib by GC- or LC-MS. Gefitinib is an EGFR inhibitor (IC50s = 0.023-0.079 μM). It inhibits colony formation of GEO colon, ZR-75-1 and MCF-10A breast, and OVCAR-3 ovarian cancer cell lines in soft agar assays (IC50s = 0.2-0.4 μM). Gefitinib (0.1 to 1 μM) induces apoptosis and inhibits EGFR autophosphorylation in the same cells. In vivo, gefitinib (1.25, 2.5, and 5 mg/kg) reduces tumor volume and increases survival in a GEO mouse xenograft model. Formulations containing gefitinib have been used in the treatment of non-small cell lung cancer (NSCLC).More related product prices
3-Chloro-4-fluoroaniline 3-Hydroxy-4-methoxybenzonitrile Gefitinib 7357-67-7 7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one 4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol 13794-72-4 3,4-Dichloroaniline 6-Hydroxy-7-methoxy-3,4-dihydroquinazolin-4-one 4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yl acetateRelated product price
- 3-Chloro-4-fluoroaniline
$5-6566.18 - 3-Hydroxy-4-methoxybenzonitrile
$6-1499.19 - Gefitinib
$5-1141
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