NSC 42834
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- $32 - $3624
- Product name: NSC 42834
- CAS: 195371-52-9
- MF: C23H24N2O
- MW: 344.45
- EINECS:
- MDL Number:MFCD00023550
- Synonyms:JAK2 Inhibitor V, Z3;NSC 42834;1-Butanone, 2-Methyl-1-phenyl-4-(2-pyridinyl)-2-[2-(2-pyridinyl)ethyl]-;2-METHYL-1-PHENYL-4-(PYRIDIN-2-YL)-2-(2-(PYRIDIN-2-YL)ETHYL)BUTAN-1-ONE;2-Methyl-1-phenyl-4-(2-pyridinyl)-2-[2-(2-pyridinyl)ethyl]-1-butanone;NSC 42834 2-Methyl-1-phenyl-4-(2-pyridinyl)-2-[2-(2-pyridinyl)ethyl]-1-butanone;JAK2 Inhibitor V, Z3, >=98%;JAK2 Inhibitor V
16 prices
Selected condition：
Brand
- AK Scientific
- ApexBio Technology
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 500mg
- 1g
- ManufacturerAK Scientific
- Product number3183AH
- Product description2-Methyl-1-phenyl-4-(pyridin-2-yl)-2-(2-(pyridin-2-yl)ethyl)butan-1-one
- Packaging100mg
- Price$1237
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number3183AH
- Product description2-Methyl-1-phenyl-4-(pyridin-2-yl)-2-(2-(pyridin-2-yl)ethyl)butan-1-one
- Packaging500mg
- Price$3624
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3514
- Product descriptionJAK2InhibitorV,Z3
- Packaging5mg
- Price$483
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17684
- Product descriptionJAK2 Inhibitor V ≥95%
- Packaging25mg
- Price$267
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17684
- Product descriptionJAK2 Inhibitor V ≥95%
- Packaging10mg
- Price$122
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17684
- Product descriptionJAK2 Inhibitor V ≥95%
- Packaging5mg
- Price$78
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17684
- Product descriptionJAK2 Inhibitor V ≥95%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-1006
- Product descriptionNSC42834 96.79%
- Packaging5mg
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-1006
- Product descriptionNSC42834 96.79%
- Packaging10mg
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-1006
- Product descriptionNSC42834 96.79%
- Packaging50mg
- Price$350
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-1006
- Product descriptionNSC42834 96.79%
- Packaging100mg
- Price$650
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31002804
- Product descriptionNSC42834 98+%
- Packaging5mg
- Price$215
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC7436
- Product descriptionJAK2InhibitorV,Z3 >98%
- Packaging100mg
- Price$500
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC7436
- Product descriptionJAK2InhibitorV,Z3 >98%
- Packaging250mg
- Price$800
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC7436
- Product descriptionJAK2InhibitorV,Z3 >98%
- Packaging1g
- Price$1500
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product number420141
- Product descriptionJAK2 Inhibitor V, Z3 - CAS 195371-52-9 - Calbiochem
- Packaging10MG
- Price$154
- Updated2023-01-07
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 3183AH | 2-Methyl-1-phenyl-4-(pyridin-2-yl)-2-(2-(pyridin-2-yl)ethyl)butan-1-one | 100mg | $1237 | 2021-12-16 | Buy |
| AK Scientific | 3183AH | 2-Methyl-1-phenyl-4-(pyridin-2-yl)-2-(2-(pyridin-2-yl)ethyl)butan-1-one | 500mg | $3624 | 2021-12-16 | Buy |
| ApexBio Technology | A3514 | JAK2InhibitorV,Z3 | 5mg | $483 | 2021-12-16 | Buy |
| Cayman Chemical | 17684 | JAK2 Inhibitor V ≥95% | 25mg | $267 | 2024-03-01 | Buy |
| Cayman Chemical | 17684 | JAK2 Inhibitor V ≥95% | 10mg | $122 | 2024-03-01 | Buy |
| Cayman Chemical | 17684 | JAK2 Inhibitor V ≥95% | 5mg | $78 | 2024-03-01 | Buy |
| Cayman Chemical | 17684 | JAK2 Inhibitor V ≥95% | 1mg | $32 | 2024-03-01 | Buy |
| ChemScene | CS-1006 | NSC42834 96.79% | 5mg | $60 | 2021-12-16 | Buy |
| ChemScene | CS-1006 | NSC42834 96.79% | 10mg | $90 | 2021-12-16 | Buy |
| ChemScene | CS-1006 | NSC42834 96.79% | 50mg | $350 | 2021-12-16 | Buy |
| ChemScene | CS-1006 | NSC42834 96.79% | 100mg | $650 | 2021-12-16 | Buy |
| Crysdot | CD31002804 | NSC42834 98+% | 5mg | $215 | 2021-12-16 | Buy |
| DC Chemicals | DC7436 | JAK2InhibitorV,Z3 >98% | 100mg | $500 | 2021-12-16 | Buy |
| DC Chemicals | DC7436 | JAK2InhibitorV,Z3 >98% | 250mg | $800 | 2021-12-16 | Buy |
| DC Chemicals | DC7436 | JAK2InhibitorV,Z3 >98% | 1g | $1500 | 2021-12-16 | Buy |
| Sigma-Aldrich | 420141 | JAK2 Inhibitor V, Z3 - CAS 195371-52-9 - Calbiochem | 10MG | $154 | 2023-01-07 | Buy |
Properties
Boiling point :520.4±50.0 °C(Predicted)
Density :1.106±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMSO: 20 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
form :Powder
pka :5.90±0.12(Predicted)
color :Colorless to light yellow
Density :1.106±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMSO: 20 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
form :Powder
pka :5.90±0.12(Predicted)
color :Colorless to light yellow
Safety Information
| Symbol(GHS): |
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| Signal word: | Danger | |||||||
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Description
Janus-associated kinases (JAKs) are cytoplasmic tyrosine kinases that are required for activating the signaling of certain cytokines and growth factor receptors. Many myeloproliferative diseases have been linked to a mutation in JAK2 in which a switch from valine to phenylalanine occurs at the 617 position (V617F). JAK2 Inhibitor V is an inhibitor of the autophosphorylation of wild type and V617F mutant forms of JAK2, displaying IC50 values between 10 and 30 μM. It has no effect on Tyk2 or c-Src kinase function. JAK2 Inhibitor V blocks the proliferation of erythroleukemia cells and human hematopoietic progenitor cells expressing JAK2-V617F.More related product prices
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$1.00 /1ASSAYS
2-METHYL-1-PHENYL-4-(PYRIDIN-2-YL)-2-(2-(PYRIDIN-2-YL)ETHYL)BUTAN-1-ONE CAS:195371-52-9
2-METHYL-1-PHENYL-4-(PYRIDIN-2-YL)-2-(2-(PYRIDIN-2-YL)ETHYL)BUTAN-1-ONE CAS:195371-52-9
