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ChemicalBook >> CAS DataBase List >> NSC781406

NSC781406

NSC781406 price.
  • $32 - $1200
  • Product name: NSC781406
  • CAS: 1676893-24-5
  • MF: C29H27F2N5O5S2
  • MW: 627.68
  • EINECS:
  • MDL Number:
  • Synonyms:NSC781406;NSC781406;NSC-781406;NSC 781406;NSC-781406;NSC 781406;Benzenesulfonamide, 2,4-difluoro-N-[2-methoxy-5-[4-[3-[4-(methylsulfonyl)-1-piperazinyl]-1-propyn-1-yl]-6-quinolinyl]-3-pyridinyl]-;NSC781406,Phosphoinositide 3-kinase,NSC 781406,NSC-781406,PI3K,Mammalian target of Rapamycin,Inhibitor,inhibit,mTOR;2,4-difluoro-N-[2-methoxy-5-[4-[3-[4-(methylsulfonyl)-1-piperazinyl]-1-propyn-1-yl]-6-quinolinyl]-3-pyridinyl]-benzenesulfonamide
Price11 Properties Safety Information Description
11 prices
Selected condition：
Brand
  • AK Scientific
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
Package
  • 1mg
  • 5mg
  • 10mg
  • 50mg
  • 100mg
  • 250mg
  • ManufacturerAK Scientific
  • Product number5398EJ
  • Product description2,4-Difluoro-N-[2-methoxy-5-[4-[3-(4-methylsulfonylpiperazin-1-yl)prop-1-ynyl]quinolin-6-yl]pyridin-3-yl]benzenesulfonamide
  • Packaging5mg
  • Price$252
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number29226
  • Product descriptionNSC 781406
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number29226
  • Product descriptionNSC 781406
  • Packaging5mg
  • Price$139
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number29226
  • Product descriptionNSC 781406
  • Packaging10mg
  • Price$261
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6958
  • Product descriptionNSC781406 99.91%
  • Packaging1mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6958
  • Product descriptionNSC781406 99.91%
  • Packaging5mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6958
  • Product descriptionNSC781406 99.91%
  • Packaging10mg
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6958
  • Product descriptionNSC781406 99.91%
  • Packaging50mg
  • Price$600
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6958
  • Product descriptionNSC781406 99.91%
  • Packaging100mg
  • Price$950
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC10484
  • Product descriptionNSC781406 >98%
  • Packaging100mg
  • Price$700
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC10484
  • Product descriptionNSC781406 >98%
  • Packaging250mg
  • Price$1200
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 5398EJ 2,4-Difluoro-N-[2-methoxy-5-[4-[3-(4-methylsulfonylpiperazin-1-yl)prop-1-ynyl]quinolin-6-yl]pyridin-3-yl]benzenesulfonamide 5mg $252 2021-12-16 Buy
Cayman Chemical 29226 NSC 781406 1mg $32 2024-03-01 Buy
Cayman Chemical 29226 NSC 781406 5mg $139 2024-03-01 Buy
Cayman Chemical 29226 NSC 781406 10mg $261 2024-03-01 Buy
ChemScene CS-6958 NSC781406 99.91% 1mg $60 2021-12-16 Buy
ChemScene CS-6958 NSC781406 99.91% 5mg $120 2021-12-16 Buy
ChemScene CS-6958 NSC781406 99.91% 10mg $200 2021-12-16 Buy
ChemScene CS-6958 NSC781406 99.91% 50mg $600 2021-12-16 Buy
ChemScene CS-6958 NSC781406 99.91% 100mg $950 2021-12-16 Buy
DC Chemicals DC10484 NSC781406 >98% 100mg $700 2021-12-16 Buy
DC Chemicals DC10484 NSC781406 >98% 250mg $1200 2021-12-16 Buy

Properties

Boiling point :775.1±70.0 °C(Predicted)
Density :1.52±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 10mg/mL; DMSO: 20mg/mL; DMSO:PBS (pH 7.2) (1:4): 0.2mg/mL
form :A solid
pka :6.23±0.40(Predicted)
color :White to off-white

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

NSC 781406 is a dual inhibitor of PI3K and mammalian target of rapamycin (mTOR; IC50s = 2.0, 9.4, 2.7, 14, and 5.4 nM for PI3Kα, PI3Kβ, PI3Kγ, PI3Kδ, and mTOR, respectively). It inhibits cell growth in the NCI-60 panel of cancer cell lines (mean GI50 = 65 nM). NSC 781406 (30 mg/kg) reduces tumor volume in a BEL-7404 hepatic cancer mouse xenograft model.

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Suppliers and manufacturers

TargetMol Chemicals Inc.
NSC781406
$58.00 /5mg
NSC781406 CAS:1676893-24-5
ATK CHEMICAL COMPANY LIMITED
InvivoChem
Aladdin Scientific Shanghai Boyle Chemical Co., Ltd. MedChemexpress LLC Shanghai Lollane Biological Technology Co.,Ltd. YouCoChem (Beijing) Chemical Technology Co., Ltd. ShangHai Biochempartner Co.,Ltd Shanghai Chaolan Chemical Technology Center