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ChemicalBook >> CAS DataBase List >> Pifithrin-α (PFTα)

Pifithrin-α (PFTα)

Pifithrin-α (PFTα) price.
  • $50 - $3108
  • Product name: Pifithrin-α (PFTα)
  • CAS: 63208-82-2
  • MF: C16H19BrN2OS
  • MW: 367.3
  • EINECS:
  • MDL Number:MFCD00417851
  • Synonyms:1-(4-METHYLPHENYL)-2-(4,5,6,7-TETRAHYDRO-2-IMINO-3(2H)-BENZOTHIAZOLYL)ETHANONE, MONOHYDROBROMIDE;Pifithrin-Hydrobromide;2-(2-imino-4,5,6,7-tetrahydrobenzothiazol-3-yl)-1-p-tolylethanone hydrobromide;PFT-α,Pifithrin-α;Zinc03874684;Ethanone, 1-(4-Methylphenyl)-2-(4,5,6,7-tetrahydro-2-iMino-3(2H)-benzothiazolyl)-, MonohydrobroMide;PFTα hydrobroMide;Pifithrin-alpha . HBr
Price39 Properties Safety Information Description
39 prices
Selected condition：
Brand
  • Adipogen Life Sciences
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Arctom
  • Axon Medchem
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Matrix Scientific
  • Sigma-Aldrich
  • TCI Chemical
  • Usbiological
Package
  • 10mM(in 1mL DMSO)
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 2x50mg
  • 100mg
  • 250mg
  • 1g
  • 5g
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-0004-M025
  • Product descriptionPifithrin-α·hydrobromide ≥98%(HPLC+NMR)
  • Packaging25mg
  • Price$160
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberX5922
  • Product descriptionPifithrin-alpha
  • Packaging50mg
  • Price$409
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberX5922
  • Product descriptionPifithrin-alpha
  • Packaging10mg
  • Price$110
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA201732
  • Product description2-(2-Imino-4,5,6,7-tetrahydrobenzothiazol-3-yl)-1-p-tolylethanoneHydrobromide 98+%
  • Packaging250mg
  • Price$312
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA201732
  • Product description2-(2-Imino-4,5,6,7-tetrahydrobenzothiazol-3-yl)-1-p-tolylethanoneHydrobromide 98+%
  • Packaging100mg
  • Price$189
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA201732
  • Product description2-(2-Imino-4,5,6,7-tetrahydrobenzothiazol-3-yl)-1-p-tolylethanoneHydrobromide 98+%
  • Packaging50mg
  • Price$123
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4206
  • Product descriptionPifithrin-α(PFTα)
  • Packaging5mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4206
  • Product descriptionPifithrin-α(PFTα)
  • Packaging10mg
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4206
  • Product descriptionPifithrin-α(PFTα)
  • Packaging10mM(in 1mL DMSO)
  • Price$121
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4206
  • Product descriptionPifithrin-α(PFTα)
  • Packaging25mg
  • Price$175
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4206
  • Product descriptionPifithrin-α(PFTα)
  • Packaging50mg
  • Price$275
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60183
  • Product descriptionPifithrin-alphaHBr
  • Packaging10mg
  • Price$198
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon1871
  • Product descriptionPifithrin-αhydrobromide-PFT-α 99%
  • Packaging50mg
  • Price$385
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon1871
  • Product descriptionPifithrin-αhydrobromide-PFT-α 99%
  • Packaging2x50mg
  • Price$616
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number13326
  • Product descriptionPifithrin-α ≥95%
  • Packaging5mg
  • Price$64
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13326
  • Product descriptionPifithrin-α ≥95%
  • Packaging10mg
  • Price$101
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CR1-0004-M025 Pifithrin-α·hydrobromide ≥98%(HPLC+NMR) 25mg $160 2021-12-16 Buy
AK Scientific X5922 Pifithrin-alpha 50mg $409 2021-12-16 Buy
AK Scientific X5922 Pifithrin-alpha 10mg $110 2021-12-16 Buy
Ambeed A201732 2-(2-Imino-4,5,6,7-tetrahydrobenzothiazol-3-yl)-1-p-tolylethanoneHydrobromide 98+% 250mg $312 2021-12-16 Buy
Ambeed A201732 2-(2-Imino-4,5,6,7-tetrahydrobenzothiazol-3-yl)-1-p-tolylethanoneHydrobromide 98+% 100mg $189 2021-12-16 Buy
Ambeed A201732 2-(2-Imino-4,5,6,7-tetrahydrobenzothiazol-3-yl)-1-p-tolylethanoneHydrobromide 98+% 50mg $123 2021-12-16 Buy
ApexBio Technology A4206 Pifithrin-α(PFTα) 5mg $50 2021-12-16 Buy
ApexBio Technology A4206 Pifithrin-α(PFTα) 10mg $75 2021-12-16 Buy
ApexBio Technology A4206 Pifithrin-α(PFTα) 10mM(in 1mL DMSO) $121 2021-12-16 Buy
ApexBio Technology A4206 Pifithrin-α(PFTα) 25mg $175 2021-12-16 Buy
ApexBio Technology A4206 Pifithrin-α(PFTα) 50mg $275 2021-12-16 Buy
Arctom CFN60183 Pifithrin-alphaHBr 10mg $198 2021-12-16 Buy
Axon Medchem Axon1871 Pifithrin-αhydrobromide-PFT-α 99% 50mg $385 2021-12-16 Buy
Axon Medchem Axon1871 Pifithrin-αhydrobromide-PFT-α 99% 2x50mg $616 2021-12-16 Buy
Cayman Chemical 13326 Pifithrin-α ≥95% 5mg $64 2024-03-01 Buy
Cayman Chemical 13326 Pifithrin-α ≥95% 10mg $101 2024-03-01 Buy
Next Last

Properties

Melting point :192.1-192.5 °C(lit.)
storage temp. :-20°C
solubility :DMSO: 20 mg/mL
form :powder
pka :9.11(at 25℃)
color :off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Pifithrin-α is an inactivator of p53 that blocks p53-dependent transcriptional activation and apoptosis. It prevents p53-mediated apoptosis induced by cytotoxic compounds in C8 cells at 10 μM and in human umbilical vein endothelial cells at 30 μM. Pifithrin-α can also protect cells from DNA damage-induced apoptosis by a p53-independent mechanism that might involve cyclin D1.

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Suppliers and manufacturers

TargetMol Chemicals Inc.
Pifithrin-α hydrobromide
$33.00 /2mg
Pifithrin-α hydrobromide CAS:63208-82-2
Hangzhou FandaChem Co.,Ltd.
ATK CHEMICAL COMPANY LIMITED
BOC Sciences
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
Career Henan Chemica Co
Dideu Industries Group Limited
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
LEAPCHEM CO., LTD.