ChemicalBook CAS DataBase List 1-AMINOHEPTANE

1-AMINOHEPTANE synthesis

7synthesis methods

Product Name:1-AMINOHEPTANE
CAS Number:111-68-2
Molecular formula:C7H17N
Molecular Weight:115.22

629-04-9 Synthesis

629-04-9
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$7.00/10g

111-68-2
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$14.00/1mL

Yield:111-68-2 85%

Reaction Conditions:

with 5-methyl-1,3,4-thiadiazol-2-amine;triethylamine in ethanol;water at 25; for 1 h;

Steps:

Typical experimental procedure for primary amines synthesis
General procedure: A mixture of alkyl halide (1.0 mmol) and 5-methyl-1,3,4-thiadiazole-2-amine (1) (1.5 mmol) were added to a flaskcontaining 3 mmol Et3N and 2 cm3 EtOH/H2O (10:1). The reaction continued at room temperature under atmosphericconditions 1 h. The reaction progress was controlled by thin-layer chromatography. Then, crude reaction mixture was purified by column chromatography (petroleum ether/ethyl acetate 1:4) to give the primary amines in good yields.

References:

Soleiman-Beigi, Mohammad;Mohammadi, Fariba [Monatshefte fur Chemie,2017,vol. 148,# 12,p. 2123 - 2128]

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