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ChemicalBook CAS DataBase List 1-Boc-3-Methoxypiperidine
146337-23-7

1-Boc-3-Methoxypiperidine synthesis

1synthesis methods
-

Yield:146337-23-7 100%

Reaction Conditions:

Stage #1: N-tert-butoxycarbonyl-3-piperidinolwith sodium hydride in tetrahydrofuran at 20; for 0.5 h;Inert atmosphere;
Stage #2: methyl iodide in tetrahydrofuran;Inert atmosphere;

References:

Lee, Seungbeom;Kim, Dae Gyu;Kim, Kyeojin;Kim, Taewoo;Lim, Semi;Kong, Hyejin;Kim, Sunghoon;Suh, Young-Ger [Journal of Medicinal Chemistry,2020,vol. 63,# 8,p. 3908 - 3914]