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ChemicalBook CAS DataBase List 1-PIPERIDIN-4-YLPYRROLIDIN-2-ONE
91596-61-1

1-PIPERIDIN-4-YLPYRROLIDIN-2-ONE synthesis

3synthesis methods
340962-88-1 Synthesis
1-(1-Benzylpiperidin-4-yl)pyrrolidin-2-one

340962-88-1
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Yield:91596-61-1 100%

Reaction Conditions:

with palladium 10% on activated carbon;ammonium formate in methanol; for 3 h;Reflux;

References:

Fujimoto, Takuya;Imaeda, Yasuhiro;Konishi, Noriko;Hiroe, Katsuhiko;Kawamura, Masaki;Textor, Garret P.;Aertgeerts, Kathleen;Kubo, Keiji [Journal of Medicinal Chemistry,2010,vol. 53,# 9,p. 3517 - 3531] Location in patent:experimental part