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10-(Oxiran-2-ylMethyl)acridin-9(10H)-one synthesis

5synthesis methods
-

Yield:150389-84-7 47%

Reaction Conditions:

Stage #1: 10H-acridin-9-onewith sodium hydride in dimethyl sulfoxide;
Stage #2: epichlorohydrin in dimethyl sulfoxide at 60 - 70;

References:

Singh, Palwinder;kaur, Jatinder;Kaur, Prabhjit;Kaur, Satwinderjeet [Bioorganic and Medicinal Chemistry,2009,vol. 17,# 6,p. 2423 - 2427] Location in patent:experimental part