6-[(2R,6S)-2,6-Dimethylmorpholin-4-yl]pyridin-3-amine dihydrochloride synthesis
1synthesis methods
- Product Name:6-[(2R,6S)-2,6-Dimethylmorpholin-4-yl]pyridin-3-amine dihydrochloride
- CAS Number:154179-39-2
- Molecular formula:C15H12Cl2N2O
- Molecular Weight:280
Yield:154179-39-2 95%
Reaction Conditions:
in ethanol;Reflux;
References:
O'Neill, Paul M.;Park, B. Kevin;Shone, Alison E.;Maggs, James L.;Roberts, Phillip;Stocks, Paul A.;Biagini, Giancarlo A.;Bray, Patrick G.;Gibbons, Peter;Berry, Neil;Winstanley, Peter A.;Mukhtar, Amira;Bonar-Law, Richard;Hindley, Stephen;Bambal, Ramesh B.;Davis, Charles B.;Bates, Martin;Hart, Timothy K.;Gresham, Stephanie L.;Lawrence, Ron M.;Brigandi, Richard A.;Gomez-delas-Heras, Federico M.;Gargallo, Domingo V.;Ward, Stephen A. [Journal of Medicinal Chemistry,2009,vol. 52,# 5,p. 1408 - 1415] Location in patent:scheme or table