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ChemicalBook CAS DataBase List 5-Aminobenzimidazole

5-Aminobenzimidazole synthesis

5synthesis methods
-

Yield:934-22-5 100%

Reaction Conditions:

with hydrogen;palladium 10% on activated carbon in methanol under 760.051 Torr; for 20 h;

Steps:

10
Example 10; 1H-Benzimidazol-5-amine A solution of 5-nitrobenzin-ddazole (10. 0 g, 61.3 mmol) in methanol (250 mL) was hydrogenated in the presence of 10% Pd/C (0. 40 g) at atmospheric pressure for 20h. The mixture was filtered through CeliteNo. and the solvent removed under reduced pressure to afford the pure product () %).

References:

CYTOPIA RESEARCH PTY LTD WO2005/66156, 2005, A1 Location in patent:Page/Page column 33

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