ChemicalBook CAS DataBase List 2-(2,3-DICHLORO-PHENYL)-THIAZOLE-4-CARBOXYLIC ACID

2-(2,3-DICHLORO-PHENYL)-THIAZOLE-4-CARBOXYLIC ACID synthesis

3synthesis methods

Product Name:2-(2,3-DICHLORO-PHENYL)-THIAZOLE-4-CARBOXYLIC ACID
CAS Number:257876-07-6
Molecular formula:C10H5Cl2NO2S
Molecular Weight:274.12

1113-59-3 Synthesis

1113-59-3
293 suppliers
$14.00/1g

84863-83-2
67 suppliers
$17.67/250mgs:

2-(2,3-DICHLORO-PHENYL)-THIAZOLE-4-CARBOXYLIC ACID

257876-07-6
19 suppliers
$75.00/10mg

Yield:257876-07-6 98%

Reaction Conditions:

in 1,4-dioxane; for 2 h;Product distribution / selectivity;Heating / reflux;

Steps:

D.1

Step 1. 2-(2,3-Dichloro-phenyl)-thiazole-4-carboxylic acid A solution of 2,3-dichloro-thiobenzamide (Maybridge plc, Tintagel, Cornwall, UK; 2.06 g, 10 mmol) and 3-bromopyruvic acid (1.67 g, 10 mmol) in dioxane (50 mL) was heated at reflux for 2 hrs. The solution was concentrated in vacuo. Water (50 mL) was added. The resulting solid was filtered and triturated with ether to give a white solid (2.68 g, 98%).

References:

US2007/167622,2007,A1 Location in patent:Page/Page column 14

175276-86-5 Synthesis

ETHYL 2-(2,3-DICHLOROPHENYL)-1,3-THIAZOLE-4-CARBOXYLATE

175276-86-5
22 suppliers
$179.00/1g

257876-07-6
19 suppliers
$75.00/10mg

References

5980-24-5 Synthesis

5980-24-5
43 suppliers
$31.80/1gm:

257876-07-6
19 suppliers
$75.00/10mg

References

2-(2,3-DICHLORO-PHENYL)-THIAZOLE-4-CARBOXYLIC ACID Related Search:

2-(3-CHLOROPHENYL)-1,3-THIAZOLE-4-CARBOXALDEHYDE 97 2-PHENYL-1,3-THIAZOLE-4-CARBOXYLIC ACID (2-PHENYL-1,3-THIAZOL-4-YL)METHANOL 2-(2-CHLORO-PHENYL)-THIAZOLE-4-CARBALDEHYDE ETHYL 2-(2,3-DICHLOROPHENYL)-1,3-THIAZOLE-4-CARBOXYLATE [2-(2-CHLORO-PHENYL)-THIAZOL-4-YL]-METHANOL