![](/CAS/GIF/6334-18-5.gif)
2,3-Dichlorobenzaldehyde synthesis
- Product Name:2,3-Dichlorobenzaldehyde
- CAS Number:6334-18-5
- Molecular formula:C7H4Cl2O
- Molecular Weight:175.01
![2,3-DICHLOROBENZYL ALCOHOL](/CAS/GIF/38594-42-2.gif)
38594-42-2
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$12.00/250mg
![2,3-Dichlorobenzaldehyde](/CAS/GIF/6334-18-5.gif)
6334-18-5
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$6.00/10g
Yield:6334-18-5 48.19 g
Reaction Conditions:
with hydrogen bromide;dihydrogen peroxide in 1,4-dioxane at 25; for 7 h;Temperature;
Steps:
1
In a 1L reactor,add 61.5 g of 2,3-dichlorotoluene, 3.075 g of azobisisobutyronitrile (5%), 215.25 g of 2-dichloroethane, heat the mixture at 75 ° C and add 44 g of bromine drop wise,reflux reaction till red bromine fades , Intermittent drip and 136.2g27.5% hydrogen peroxide continues to react till red bromine no longer generates. Add a 49.2g30% aqueous solution of sodium carbonate to the reaction solution, reflux reaction for 8 h ,at the same time recover1,2-dichloroethane.The hydrolyzate is heated and filtered at 80° C, into organic phase add 246g 1,4-Dioxane , add 40% of the catalyst HBr6.15g, add 27.5% hydrogen peroxide 38.3g,react at 25 ° C for 7 h. The reaction system is extracted three times with 1,2-dichloroethane,the organic phase is concentrated and obtained crude 2,3-dichlorobenzaldehyde, re-crystallization from ethanol and obtained 48.19 g of 2,3-dichlorobenzaldehyde, GC purity is 99.26% and yield is 72.1%.
References:
Lianyungang Industry Investment Group Co., Ltd.;Jiang Honglai;Jiang Xiao;Han Yong;Zang Han;Zhu Chengjie;Shen Weiwei CN107032968, 2017, A Location in patent:Paragraph 0015; 0017; 0018; 0019; 0022
![2,3-Dichlorotoluene](/CAS/GIF/32768-54-0.gif)
32768-54-0
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$9.00/25g
![2,3-Dichlorobenzaldehyde](/CAS/GIF/6334-18-5.gif)
6334-18-5
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$6.00/10g
![2,3-DICHLOROBENZALDOXIME](/CAS/GIF/4414-54-4.gif)
4414-54-4
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$43.00/1g
![2,3-Dichlorobenzaldehyde](/CAS/GIF/6334-18-5.gif)
6334-18-5
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$6.00/10g
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288-43-7
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1820-80-0
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![3,4-Dichlorobenzaldehyde](/CAS/GIF/6287-38-3.gif)
6287-38-3
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$8.00/10g
![2,3-Dichlorobenzaldehyde](/CAS/GIF/6334-18-5.gif)
6334-18-5
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![1,2-Dichlorobenzene](/CAS/GIF/95-50-1.gif)
95-50-1
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![2,3-Dichlorobenzaldehyde](/CAS/GIF/6334-18-5.gif)
6334-18-5
392 suppliers
$6.00/10g