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ChemicalBook CAS DataBase List 2-(4-fluorophenyl)thiazole

2-(4-fluorophenyl)thiazole synthesis

3synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; silver hexafluoroantimonate / 1,2-dichloro-ethane / 24 h / 20 °C / Inert atmosphere
2: samarium diiodide; N,N,N,N,N,N-hexamethylphosphoric triamide / tetrahydrofuran / 2 h / 20 °C / Inert atmosphere

References:

Chen, Lei;Peng, Rui-Jun;Zhang, Xue-Jing;Yan, Ming;Chan, Albert S. C. [Journal of Organic Chemistry,2021,vol. 86,# 15,p. 10177 - 10189]