![](/CAS/GIF/53662-83-2.gif)
2,5-FURANDICARBOXYLIC ACID DIETHYL ESTER synthesis
- Product Name:2,5-FURANDICARBOXYLIC ACID DIETHYL ESTER
- CAS Number:53662-83-2
- Molecular formula:C10H12O5
- Molecular Weight:212.2
![2,5-Furandicarboxylic acid](/CAS/GIF/3238-40-2.gif)
3238-40-2
449 suppliers
$6.00/1g
![Ethanol](/CAS/GIF/64-17-5.gif)
64-17-5
706 suppliers
$10.00/50g
![2,5-FURANDICARBOXYLIC ACID DIETHYL ESTER](/CAS/GIF/53662-83-2.gif)
53662-83-2
115 suppliers
$6.00/250mg
Yield: 98%
Reaction Conditions:
with sulfuric acid in water at 78; for 67 h;Dean-Stark;
Steps:
12 Synthesis of 2,5-diethyl-2, 5-furandicarboxylate
2,5-furandicarboxylic acid (25.18 g; 160 mmol) was added to ethanol (1,800 mL).Aqueous sulfuric acid (1.32 mL) was added. The mixture was heated at reflux (about78°C) for 67 hours, during which time water was removed from the reaction by the use ofa Dean-Stark apparatus. The reaction progress was monitored using NMR spectroscopy. After the 2,5-diethyl-2,5-furandicarboxylate had been formed in >97% purity by NMR, the reaction mixture was allowed to cool to ambient temperature and was extracted with 2- methyltetrahydrofuran. The combined organic layers were washed with a saturated aqueous brine solution and deionised water, and dried (Mg504). The organics werefiltered and the volatiles were removed in vacuo to afford the title compound (26.77 g; 130 mmol; >98% conversion).
References:
BIOME BIOPLASTICS LIMITED;LAW, Paul;MINES, Paul;CARNELL, Andrew;MCKENNA, Shane WO2016/202858, 2016, A1 Location in patent:Page/Page column 57
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6132-37-2
68 suppliers
$27.00/250mg
![Ethanol](/CAS/GIF/64-17-5.gif)
64-17-5
706 suppliers
$10.00/50g
201230-82-2
1 suppliers
inquiry
![2,5-FURANDICARBOXYLIC ACID DIETHYL ESTER](/CAS/GIF/53662-83-2.gif)
53662-83-2
115 suppliers
$6.00/250mg
![2,5-Furandicarboxylic acid](/CAS/GIF/3238-40-2.gif)
3238-40-2
449 suppliers
$6.00/1g
![Ethanol](/CAS/GIF/64-17-5.gif)
64-17-5
706 suppliers
$10.00/50g
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32933-01-0
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53662-83-2
115 suppliers
$6.00/250mg
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88-14-2
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64-17-5
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124-38-9
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![2,5-FURANDICARBOXYLIC ACID DIETHYL ESTER](/CAS/GIF/53662-83-2.gif)
53662-83-2
115 suppliers
$6.00/250mg
![Ethanol](/CAS/GIF/64-17-5.gif)
64-17-5
706 suppliers
$10.00/50g
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67-66-3
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![2,5-FURANDICARBOXYLIC ACID DIETHYL ESTER](/CAS/GIF/53662-83-2.gif)
53662-83-2
115 suppliers
$6.00/250mg