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ChemicalBook CAS DataBase List 2-AMino-3-forMyl-4-chloropyridine

2-AMino-3-forMyl-4-chloropyridine synthesis

3synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: n-butyllithium / hexane / 1.5 h / -78 - -72 °C
1.2: 2 h / -75 - -72 °C
2.1: trifluoroacetic acid / dichloromethane / 21.5 h / 0 - 20 °C

References:

BOEHRINGER INGELHEIM INTERNATIONAL GMBH;FADER, Lee;BEAULIEU, Pierre Louis;BAILEY, Murray;BILODEAU, François;CARSON, Rebekah;GIROUX, André;GODBOUT, Cédrickx;HUCKE, Oliver;JOLY, Marc-André;LEBLANC, Mélissa;LEPAGE, Olivier;MOREAU, Benoît;NAUD, Julie;POIRIER, Martin;VILLEMURE, Elisia WO2013/152065, 2013, A2