![](/CAS/GIF/33264-82-3.gif)
2-AMINO-5-FLUOROBENZENETHIOL synthesis
- Product Name:2-AMINO-5-FLUOROBENZENETHIOL
- CAS Number:33264-82-3
- Molecular formula:C6H6FNS
- Molecular Weight:143.18
![Benzothiazole, 6-fluoro-2-methyl- (7CI,8CI,9CI)](/CAS/GIF/399-73-5.gif)
399-73-5
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$51.00/250mg
![2-AMINO-5-FLUOROBENZENETHIOL](/CAS/GIF/33264-82-3.gif)
33264-82-3
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$45.00/25mg
Yield:33264-82-3 96%
Reaction Conditions:
with water;sodium hydroxide in ethylene glycol at 140; for 6 h;
Steps:
89.1 Step 1: 2-Amino-S -fluorobenzenethiol (2):
To a solution of 6-fluoro-2-methylbenzo[djthiazole 1 (2 g, 11.96 mmol) in ethylene glycol (10 mL) was added 8 N NaOH (8 mL). The resulting reaction mixture was stirred at 140°C for 6 h. Progress of the reaction was monitored by TLC. After completion, the reaction mixture was cooled to room temperature; acidified with iN HC1 up to pH=6 and extracted with ethyl acetate. The combined organic layer was dried over anhydrous Na2SO4 filtered and concentrated under reduced pressure to afford the title compound 2 as yellow solid (1.65 g, yield96%).
References:
WO2016/197078,2016,A1 Location in patent:Paragraph 822-823
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348-40-3
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$9.00/5g
![2-AMINO-5-FLUOROBENZENETHIOL](/CAS/GIF/33264-82-3.gif)
33264-82-3
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$45.00/25mg
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63755-07-7
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33264-82-3
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$45.00/25mg
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$5.00/5G
![2-AMINO-5-FLUOROBENZENETHIOL](/CAS/GIF/33264-82-3.gif)
33264-82-3
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$45.00/25mg
![6-FLUOROBENZOTHIAZOLE](/CAS/GIF/118220-71-6.gif)
118220-71-6
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![2-AMINO-5-FLUOROBENZENETHIOL](/CAS/GIF/33264-82-3.gif)
33264-82-3
31 suppliers
$45.00/25mg