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ChemicalBook CAS DataBase List 2-Benzylaminopyridine
6935-27-9

2-Benzylaminopyridine synthesis

13synthesis methods
-

Yield: 100%

Reaction Conditions:

with dichloro-[1,3-bis(4-tert-butylbenzyl)perhydrobenzimidazol-2-ylidene](p-cymene)ruthenium(II);potassium tert-butylate at 120; for 24 h;Inert atmosphere;Schlenk technique;Sealed tube;Reagent/catalyst;

Steps:

2.5. General procedure for the Nalkylation of amines with alcohols
General procedure: Under an inert atmosphere, KOBut (1 mmol), the aromatic amine (1 mmol), the alcohol derivative (1.5 mmol) and the Ru-NHC complex (2.5 mol%) were added to a Schlenk tube. The sealed Schlenk tube was stirred at 120 °C for 24 h. At the end of the reaction,the mixture was cooled to room temperature, CH2Cl2 (2 mL)was added and the resulting solution was filtered through a shortpad of SiO2. The filtrate was analysed by GC-MS with the calibrations based on dodecane.

References:

Yiğit, Beyhan;Özge Karaca, Emine;Yiğit, Murat;Gürbüz, Nevin;Arslan, Hakan;Özdemir, İsmail [Polyhedron,2020,vol. 175,art. no. 114234]

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