
2-BROMO-3-(CHLOROMETHYL)PYRIDINE synthesis
- Product Name:2-BROMO-3-(CHLOROMETHYL)PYRIDINE
- CAS Number:89581-84-0
- Molecular formula:C6H5Cl2N
- Molecular Weight:162.02

18368-76-8
320 suppliers
$8.00/1g

89581-84-0
98 suppliers
$49.00/1g
Yield: 87.4%
Reaction Conditions:
with chlorine at 110; for 30 h;Temperature;
Steps:
2.A A. Chlorination:
480 g of 2-chloro-3-methylpyridine (99%) was added to the four-necked flask,Stirring,Warm up to 110°C, Continuously pass the chlorine gas of 40g/h for 30h,The reaction is over.Reagent distillation,The distillation tower is 1.5m high.The tower diameter is 0.02m.Glass spring packing(0.5*4mm),The reflux ratio is 3:1.Collect 94-96°C/400-pa fractions into 2-chloro-3-chloromethylpyridine 533g.99% purityYield 87.4%.
References:
Nanjing Hong Sun Biochemical Co., Ltd.;Chen Honglong;Mu Dengyou;Yue Ruikuan;Xue Yi;Zhong Jingsong CN107501171, 2017, A Location in patent:Paragraph 0029; 0030; 0038; 0039; 0040

42330-59-6
272 suppliers
$6.00/1g

89581-84-0
98 suppliers
$49.00/1g

59-67-6
1128 suppliers
$7.00/25g

89581-84-0
98 suppliers
$49.00/1g

49609-84-9
245 suppliers
$20.00/5g

89581-84-0
98 suppliers
$49.00/1g

2942-59-8
825 suppliers
$5.00/25g

89581-84-0
98 suppliers
$49.00/1g