![](/CAS/GIF/2106-50-5.gif)
2-Chloro-4-fluoronitrobenzene synthesis
- Product Name:2-Chloro-4-fluoronitrobenzene
- CAS Number:2106-50-5
- Molecular formula:C6H3ClFNO2
- Molecular Weight:175.54
![1-Chloro-3-fluorobenzene](/CAS/GIF/625-98-9.gif)
625-98-9
180 suppliers
$14.00/25g
![2-Chloro-4-fluoronitrobenzene](/CAS/GIF/2106-50-5.gif)
2106-50-5
172 suppliers
$14.00/1g
Yield:2106-50-5 16.7%
Reaction Conditions:
with sulfuric acid;nitric acid in hexane;benzene
Steps:
37.a (a)
(a) 3-Chloro-4-nitrofluorobenzene m-Chlorofluorobenzene (240 g. 1.85 moles) is added to a mixture of sulfuric acid (185 g. 1.85 moles) and nitric acid (166 g., 1.85 moles) at -5° C. in 3.5 hours, stirred 13 hours, then benzene (200 ml.) and hexane (200 ml.) ae added. The extract is washed with water (1+300 ml.), sodium carbonate solution (1*300 ml.), and water (1*300 ml.), dried and the solvents removed. The residue is distilled to give 138 g. of mixed isomers. The 4-nitro isomer crystallizes and is filtered off to give 3-chloro-4-nitrofluorobenzene (51 g. 16.7%) m.p. 36°-38° C.
References:
Rohm and Haas Company US4330324, 1982, A
![2,4-Dichloronitrobenzene](/CAS/GIF/611-06-3.gif)
611-06-3
7 suppliers
$15.00/25g
![2-Chloro-4-fluoronitrobenzene](/CAS/GIF/2106-50-5.gif)
2106-50-5
172 suppliers
$14.00/1g
![2,4-Difluoronitrobenzene](/CAS/GIF/446-35-5.gif)
446-35-5
420 suppliers
$5.00/10g
![4-Chloro-2-fluoronitrobenzene](/CAS/GIF/700-37-8.gif)
700-37-8
202 suppliers
$9.00/1g
![5-Fluoro-2-nitrobenzoic acid](/CAS/GIF/320-98-9.gif)
320-98-9
283 suppliers
$8.00/5g
![2-Chloro-4-fluoronitrobenzene](/CAS/GIF/2106-50-5.gif)
2106-50-5
172 suppliers
$14.00/1g
![2,4-Dichloronitrobenzene](/CAS/GIF/611-06-3.gif)
611-06-3
7 suppliers
$15.00/25g
![2-Chloro-4-fluoronitrobenzene](/CAS/GIF/2106-50-5.gif)
2106-50-5
172 suppliers
$14.00/1g